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Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.
Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr. Yoo EJ, et al. Among authors: lam h. Br J Pharmacol. 2017 Dec;174(23):4383-4395. doi: 10.1111/bph.14040. Epub 2017 Nov 12. Br J Pharmacol. 2017. PMID: 28921504 Free PMC article.
Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension.
Nishida K, Brune KA, Putcha N, Mandke P, O'Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye VK. Nishida K, et al. Among authors: lam h. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L581-L591. doi: 10.1152/ajplung.00074.2017. Epub 2017 Jun 22. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28642260 Free PMC article.
A nonapoptotic endothelial barrier-protective role for caspase-3.
Suresh K, Carino K, Johnston L, Servinsky L, Machamer CE, Kolb TM, Lam H, Dudek SM, An SS, Rane MJ, Shimoda LA, Damarla M. Suresh K, et al. Among authors: lam h. Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1118-L1126. doi: 10.1152/ajplung.00487.2018. Epub 2019 Mar 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30908935 Free PMC article.
The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, Liggett SB, Panettieri RA Jr, Dong X, An SS. Huang J, et al. Among authors: lam h. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28485-28495. doi: 10.1073/pnas.2003111117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097666 Free PMC article.
AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination.
Haffner MC, Esopi DM, Chaux A, Gürel M, Ghosh S, Vaghasia AM, Tsai H, Kim K, Castagna N, Lam H, Hicks J, Wyhs N, Biswal Shinohara D, Hurley PJ, Simons BW, Schaeffer EM, Lotan TL, Isaacs WB, Netto GJ, De Marzo AM, Nelson WG, An SS, Yegnasubramanian S. Haffner MC, et al. Among authors: lam h. Nat Commun. 2017 Jul 26;8(1):142. doi: 10.1038/s41467-017-00084-8. Nat Commun. 2017. PMID: 28747635 Free PMC article.
Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates.
De K, Belardinelli JM, Pandurangan AP, Ehianeta T, Lian E, Palčeková Z, Lam H, Gonzalez-Juarrero M, Bryant JM, Blundell TL, Parkhill J, Floto RA, Lowary TL, Wheat WH, Jackson M. De K, et al. Among authors: lam h. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2403206121. doi: 10.1073/pnas.2403206121. Epub 2024 Apr 17. Proc Natl Acad Sci U S A. 2024. PMID: 38630725
1,948 results