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p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Quiñones M, Al-Massadi O, Folgueira C, Bremser S, Gallego R, Torres-Leal L, Haddad-Tóvolli R, García-Caceres C, Hernandez-Bautista R, Lam BYH, Beiroa D, Sanchez-Rebordelo E, Senra A, Malagon JA, Valerio P, Fondevila MF, Fernø J, Malagon MM, Contreras R, Pfluger P, Brüning JC, Yeo G, Tschöp M, Diéguez C, López M, Claret M, Kloppenburg P, Sabio G, Nogueiras R. Quiñones M, et al. Among authors: lam byh. Nat Commun. 2018 Aug 24;9(1):3432. doi: 10.1038/s41467-018-05711-6. Nat Commun. 2018. PMID: 30143607 Free PMC article.
Thyroid Hormone Receptor Beta in the Ventromedial Hypothalamus Is Essential for the Physiological Regulation of Food Intake and Body Weight.
Hameed S, Patterson M, Dhillo WS, Rahman SA, Ma Y, Holton C, Gogakos A, Yeo GSH, Lam BYH, Polex-Wolf J, Fenske W, Bell J, Anastasovska J, Samarut J, Bloom SR, Bassett JHD, Williams GR, Gardiner JV. Hameed S, et al. Among authors: lam byh. Cell Rep. 2017 Jun 13;19(11):2202-2209. doi: 10.1016/j.celrep.2017.05.066. Cell Rep. 2017. PMID: 28614708 Free PMC article.
Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Larder R, Sim MFM, Gulati P, Antrobus R, Tung YCL, Rimmington D, Ayuso E, Polex-Wolf J, Lam BYH, Dias C, Logan DW, Virtue S, Bosch F, Yeo GSH, Saudek V, O'Rahilly S, Coll AP. Larder R, et al. Among authors: lam byh. Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):9421-9426. doi: 10.1073/pnas.1707310114. Epub 2017 Aug 15. Proc Natl Acad Sci U S A. 2017. PMID: 28811369 Free PMC article.
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance.
Al-Massadi O, Quiñones M, Clasadonte J, Hernandez-Bautista R, Romero-Picó A, Folgueira C, Morgan DA, Kalló I, Heras V, Senra A, Funderburk SC, Krashes MJ, Souto Y, Fidalgo M, Luquet S, Chee MJ, Imbernon M, Beiroa D, García-Caballero L, Gallego R, Lam BYH, Yeo G, Lopez M, Liposits Z, Rahmouni K, Prevot V, Dieguez C, Nogueiras R. Al-Massadi O, et al. Among authors: lam byh. Diabetes. 2019 Dec;68(12):2210-2222. doi: 10.2337/db19-0029. Epub 2019 Sep 16. Diabetes. 2019. PMID: 31530579 Free PMC article.
84 results