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CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes.
Narsale A, Lam B, Moya R, Lu T, Mandelli A, Gotuzzo I, Pessina B, Giamporcaro G, Geoffrey R, Buchanan K, Harris M, Bergot AS, Thomas R, Hessner MJ, Battaglia M, Serti E, Davies JD. Narsale A, et al. Among authors: lam b. JCI Insight. 2021 Jan 25;6(2):e136114. doi: 10.1172/jci.insight.136114. JCI Insight. 2021. PMID: 33301420 Free PMC article.
Th2 cell clonal expansion at diagnosis in human type 1 diabetes.
Narsale A, Almanza F, Tran T, Lam B, Seo D, Vu A, Long SA, Cooney L, Serti E, Davies JD. Narsale A, et al. Among authors: lam b. Clin Immunol. 2023 Dec;257:109829. doi: 10.1016/j.clim.2023.109829. Epub 2023 Oct 29. Clin Immunol. 2023. PMID: 37907122 Free article.
Gene Editing for CEP290-Associated Retinal Degeneration.
Pierce EA, Aleman TS, Jayasundera KT, Ashimatey BS, Kim K, Rashid A, Jaskolka MC, Myers RL, Lam BL, Bailey ST, Comander JI, Lauer AK, Maguire AM, Pennesi ME. Pierce EA, et al. N Engl J Med. 2024 May 6. doi: 10.1056/NEJMoa2309915. Online ahead of print. N Engl J Med. 2024. PMID: 38709228
[Progress in lipoarabinomannan antigen detection for tuberculosis diagnosis in people living with HIV/AIDS].
Wang MJ, Li F. Wang MJ, et al. Zhonghua Jie He He Hu Xi Za Zhi. 2024 May 12;47(5):475-480. doi: 10.3760/cma.j.cn112147-20231114-00310. Zhonghua Jie He He Hu Xi Za Zhi. 2024. PMID: 38706072 Review. Chinese.
Early TB screening in PLWHA is a key intervention to reduce transmission and control disease progression. Lipoarabinomannan (LAM) is a glycolipid of Mycobacterium tuberculosis (MTB) that can be detected in the urine of tuberculosis patients. ...
Early TB screening in PLWHA is a key intervention to reduce transmission and control disease progression. Lipoarabinomannan (LAM) is …
Recent advances in the development of DprE1 inhibitors using AI/CADD approaches.
Chen K, Xu R, Hu X, Li D, Hou T, Kang Y. Chen K, et al. Drug Discov Today. 2024 Apr 25;29(6):103987. doi: 10.1016/j.drudis.2024.103987. Online ahead of print. Drug Discov Today. 2024. PMID: 38670256 Review.
The flavoenzyme decaprenylphosphoryl-beta-d-ribose 2'-oxidase (DprE1) plays a crucial part in the biosynthesis of lipoarabinomannan and arabinogalactan for the cell wall of Mtb and represents a promising target for anti-TB drug development. ...
The flavoenzyme decaprenylphosphoryl-beta-d-ribose 2'-oxidase (DprE1) plays a crucial part in the biosynthesis of lipoarabinomannan a …
Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase.
Baltgalvis KA, Lamb KN, Symons KT, Wu CC, Hoffman MA, Snead AN, Song X, Glaza T, Kikuchi S, Green JC, Rogness DC, Lam B, Rodriguez-Aguirre ME, Woody DR, Eissler CL, Rodiles S, Negron SM, Bernard SM, Tran E, Pollock J, Tabatabaei A, Contreras V, Williams HN, Pastuszka MK, Sigler JJ, Pettazzoni P, Rudolph MG, Classen M, Brugger D, Claiborne C, Plancher JM, Cuartas I, Seoane J, Burgess LE, Abraham RT, Weinstein DS, Simon GM, Patricelli MP, Kinsella TM. Baltgalvis KA, et al. Nature. 2024 May;629(8011):435-442. doi: 10.1038/s41586-024-07318-y. Epub 2024 Apr 24. Nature. 2024. PMID: 38658751
2,470 results