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Drug treatments for covid-19: living systematic review and network meta-analysis.
Siemieniuk RA, Bartoszko JJ, Zeraatkar D, Kum E, Qasim A, Martinez JPD, Izcovich A, Lamontagne F, Han MA, Agarwal A, Agoritsas T, Azab M, Bravo G, Chu DK, Couban R, Devji T, Escamilla Z, Foroutan F, Gao Y, Ge L, Ghadimi M, Heels-Ansdell D, Honarmand K, Hou L, Ibrahim Q, Khamis A, Lam B, Mansilla C, Loeb M, Miroshnychenko A, Marcucci M, McLeod SL, Motaghi S, Murthy S, Mustafa RA, Pardo-Hernandez H, Rada G, Rizwan Y, Saadat P, Switzer C, Thabane L, Tomlinson G, Vandvik PO, Vernooij RW, Viteri-García A, Wang Y, Yao L, Zhao Y, Guyatt GH, Brignardello-Petersen R. Siemieniuk RA, et al. Among authors: lam b. BMJ. 2020 Jul 30;370:m2980. doi: 10.1136/bmj.m2980. BMJ. 2020. PMID: 32732190 Free PMC article. Updated.
Gene Editing for CEP290-Associated Retinal Degeneration.
Pierce EA, Aleman TS, Jayasundera KT, Ashimatey BS, Kim K, Rashid A, Jaskolka MC, Myers RL, Lam BL, Bailey ST, Comander JI, Lauer AK, Maguire AM, Pennesi ME. Pierce EA, et al. N Engl J Med. 2024 May 6. doi: 10.1056/NEJMoa2309915. Online ahead of print. N Engl J Med. 2024. PMID: 38709228
[Progress in lipoarabinomannan antigen detection for tuberculosis diagnosis in people living with HIV/AIDS].
Wang MJ, Li F. Wang MJ, et al. Zhonghua Jie He He Hu Xi Za Zhi. 2024 May 12;47(5):475-480. doi: 10.3760/cma.j.cn112147-20231114-00310. Zhonghua Jie He He Hu Xi Za Zhi. 2024. PMID: 38706072 Review. Chinese.
Early TB screening in PLWHA is a key intervention to reduce transmission and control disease progression. Lipoarabinomannan (LAM) is a glycolipid of Mycobacterium tuberculosis (MTB) that can be detected in the urine of tuberculosis patients. ...
Early TB screening in PLWHA is a key intervention to reduce transmission and control disease progression. Lipoarabinomannan (LAM) is …
Recent advances in the development of DprE1 inhibitors using AI/CADD approaches.
Chen K, Xu R, Hu X, Li D, Hou T, Kang Y. Chen K, et al. Drug Discov Today. 2024 Apr 25;29(6):103987. doi: 10.1016/j.drudis.2024.103987. Online ahead of print. Drug Discov Today. 2024. PMID: 38670256 Review.
The flavoenzyme decaprenylphosphoryl-beta-d-ribose 2'-oxidase (DprE1) plays a crucial part in the biosynthesis of lipoarabinomannan and arabinogalactan for the cell wall of Mtb and represents a promising target for anti-TB drug development. ...
The flavoenzyme decaprenylphosphoryl-beta-d-ribose 2'-oxidase (DprE1) plays a crucial part in the biosynthesis of lipoarabinomannan a …
2,471 results