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Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases.
Lim M, Puttick S, Houston ZH, Thurecht KJ, Kalita-de Croft P, Mahler S, Rose SE, Jeffree RL, Mazzieri R, Dolcetti R, Lakhani SR, Saunus JM. Lim M, et al. Among authors: lakhani sr. Int J Mol Sci. 2019 Mar 14;20(6):1280. doi: 10.3390/ijms20061280. Int J Mol Sci. 2019. PMID: 30875730 Free PMC article. Review.
Molecular aspects of breast cancer metastasis to the brain.
Saunus JM, Momeny M, Simpson PT, Lakhani SR, Da Silva L. Saunus JM, et al. Among authors: lakhani sr. Genet Res Int. 2011;2011:219189. doi: 10.4061/2011/219189. Epub 2011 Nov 29. Genet Res Int. 2011. PMID: 22567347 Free PMC article.
In vitro analysis of breast cancer cell line tumourspheres and primary human breast epithelia mammospheres demonstrates inter- and intrasphere heterogeneity.
Smart CE, Morrison BJ, Saunus JM, Vargas AC, Keith P, Reid L, Wockner L, Askarian-Amiri M, Sarkar D, Simpson PT, Clarke C, Schmidt CW, Reynolds BA, Lakhani SR, Lopez JA. Smart CE, et al. Among authors: lakhani sr. PLoS One. 2013 Jun 4;8(6):e64388. doi: 10.1371/journal.pone.0064388. Print 2013. PLoS One. 2013. PMID: 23750209 Free PMC article.
Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines.
Momeny M, Saunus JM, Marturana F, McCart Reed AE, Black D, Sala G, Iacobelli S, Holland JD, Yu D, Da Silva L, Simpson PT, Khanna KK, Chenevix-Trench G, Lakhani SR. Momeny M, et al. Among authors: lakhani sr. Oncotarget. 2015 Feb 28;6(6):3932-46. doi: 10.18632/oncotarget.2846. Oncotarget. 2015. PMID: 25668816 Free PMC article.
Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.
Bessette DC, Tilch E, Seidens T, Quinn MC, Wiegmans AP, Shi W, Cocciardi S, McCart-Reed A, Saunus JM, Simpson PT, Grimmond SM, Lakhani SR, Khanna KK, Waddell N, Al-Ejeh F, Chenevix-Trench G. Bessette DC, et al. Among authors: lakhani sr. PLoS One. 2015 May 13;10(5):e0125232. doi: 10.1371/journal.pone.0125232. eCollection 2015. PLoS One. 2015. PMID: 25969993 Free PMC article.
Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.
Saunus JM, Quinn MC, Patch AM, Pearson JV, Bailey PJ, Nones K, McCart Reed AE, Miller D, Wilson PJ, Al-Ejeh F, Mariasegaram M, Lau Q, Withers T, Jeffree RL, Reid LE, Da Silva L, Matsika A, Niland CM, Cummings MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Wani S, Anderson MJ, Fink JL, Holmes O, Kazakoff S, Leonard C, Newell F, Taylor D, Waddell N, Wood S, Xu Q, Kassahn KS, Narayanan V, Taib NA, Teo SH, Chow YP, kConFab, Jat PS, Brandner S, Flanagan AM, Khanna KK, Chenevix-Trench G, Grimmond SM, Simpson PT, Waddell N, Lakhani SR. Saunus JM, et al. Among authors: lakhani sr. J Pathol. 2015 Nov;237(3):363-78. doi: 10.1002/path.4583. Epub 2015 Aug 19. J Pathol. 2015. PMID: 26172396
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.
Zhang L, Zhang S, Yao J, Lowery FJ, Zhang Q, Huang WC, Li P, Li M, Wang X, Zhang C, Wang H, Ellis K, Cheerathodi M, McCarty JH, Palmieri D, Saunus J, Lakhani S, Huang S, Sahin AA, Aldape KD, Steeg PS, Yu D. Zhang L, et al. Nature. 2015 Nov 5;527(7576):100-104. doi: 10.1038/nature15376. Epub 2015 Oct 19. Nature. 2015. PMID: 26479035 Free PMC article.
Novel highly specific anti-periostin antibodies uncover the functional importance of the fascilin 1-1 domain and highlight preferential expression of periostin in aggressive breast cancer.
Field S, Uyttenhove C, Stroobant V, Cheou P, Donckers D, Coutelier JP, Simpson PT, Cummings MC, Saunus JM, Reid LE, Kutasovic JR, McNicol AM, Kim BR, Kim JH, Lakhani SR, Neville AM, Van Snick J, Jat PS. Field S, et al. Among authors: lakhani sr. Int J Cancer. 2016 Apr 15;138(8):1959-70. doi: 10.1002/ijc.29946. Epub 2015 Dec 21. Int J Cancer. 2016. PMID: 26619948 Free article.
396 results