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Classification of Cushing's syndrome PKAc mutants based upon their ability to bind PKI.
Biochem J. 2023 Jun 28;480(12):875-890. doi: 10.1042/BCJ20230183.
Biochem J. 2023.
PMID: 37306403
Mislocalization of protein kinase A drives pathology in Cushing's syndrome.
Omar MH, Byrne DP, Jones KN, Lakey TM, Collins KB, Lee KS, Daly LA, Forbush KA, Lau HT, Golkowski M, McKnight GS, Breault DT, Lefrançois-Martinez AM, Martinez A, Eyers CE, Baird GS, Ong SE, Smith FD, Eyers PA, Scott JD.
Omar MH, et al. Among authors: lakey tm.
Cell Rep. 2022 Jul 12;40(2):111073. doi: 10.1016/j.celrep.2022.111073.
Cell Rep. 2022.
PMID: 35830806
Free PMC article.
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Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs.
Omar MH, Byrne DP, Shrestha S, Lakey TM, Lee KS, Lauer SM, Collins KB, Daly LA, Eyers CE, Baird GS, Ong SE, Kannan N, Eyers PA, Scott JD.
Omar MH, et al. Among authors: lakey tm.
Sci Adv. 2024 Feb 23;10(8):eadl1258. doi: 10.1126/sciadv.adl1258. Epub 2024 Feb 21.
Sci Adv. 2024.
PMID: 38381834
Free PMC article.
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