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Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition.
Sheppard SE, March ME, Seiler C, Matsuoka LS, Kim SE, Kao C, Rubin AI, Battig MR, Khalek N, Schindewolf E, O'Connor N, Pinto E, Priestley JR, Sanders VR, Niazi R, Ganguly A, Hou C, Slater D, Frieden IJ, Huynh T, Shieh JT, Krantz ID, Guerrero JC, Surrey LF, Biko DM, Laje P, Castelo-Soccio L, Nakano TA, Snyder K, Smith CL, Li D, Dori Y, Hakonarson H. Sheppard SE, et al. Among authors: laje p. JCI Insight. 2023 May 8;8(9):e155888. doi: 10.1172/jci.insight.155888. JCI Insight. 2023. PMID: 37154160 Free PMC article.
Pathogenic variants in PIK3CA are associated with clinical phenotypes of kaposiform lymphangiomatosis, generalized lymphatic anomaly, and central conducting lymphatic anomaly.
Grenier JM, Borst AJ, Sheppard SE, Snyder KM, Li D, Surrey LF, Al-Ibraheemi A, Weber DR, Treat JR, Smith CL, Laje P, Dori Y, Adams DM, Acord M, Srinivasan AS. Grenier JM, et al. Among authors: laje p. Pediatr Blood Cancer. 2023 May 17:e30419. doi: 10.1002/pbc.30419. Online ahead of print. Pediatr Blood Cancer. 2023. PMID: 37194624
Report of IPEG 2023 Meeting.
Laje P. Laje P. J Pediatr Surg. 2024 Mar;59(3):355-356. doi: 10.1016/j.jpedsurg.2023.10.052. Epub 2023 Oct 29. J Pediatr Surg. 2024. PMID: 37968155 No abstract available.
Lung biopsy in infants with severe bronchopulmonary dysplasia.
Callaway DA, Wang Y, Lingappan K, Pogoriler JE, Laje P, Nilan K, Kirpalani H, Zhang H. Callaway DA, et al. Among authors: laje p. Pediatr Pulmonol. 2023 Jul;58(7):2068-2075. doi: 10.1002/ppul.26433. Epub 2023 May 3. Pediatr Pulmonol. 2023. PMID: 37133233
JPS Open: The Beginning of a New Era.
Holcomb GW, Tam PKH, Pakarinen M, Davenport M, Ponsky T, Laje P. Holcomb GW, et al. Among authors: laje p. J Pediatr Surg. 2022 Nov;57(11):491. doi: 10.1016/j.jpedsurg.2022.09.006. J Pediatr Surg. 2022. PMID: 36243466 No abstract available.
79 results