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A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children.
Roslund MI, Parajuli A, Hui N, Puhakka R, Grönroos M, Soininen L, Nurminen N, Oikarinen S, Cinek O, Kramná L, Schroderus AM, Laitinen OH, Kinnunen T, Hyöty H, Sinkkonen A; ADELE research group. Roslund MI, et al. Among authors: laitinen oh. Ecotoxicol Environ Saf. 2022 Sep 1;242:113900. doi: 10.1016/j.ecoenv.2022.113900. Epub 2022 Aug 3. Ecotoxicol Environ Saf. 2022. PMID: 35930838 Free article. Clinical Trial.
Human enterovirus 71 strains in the background population and in hospital patients in Finland.
Honkanen H, Oikarinen S, Pakkanen O, Ruokoranta T, Pulkki MM, Laitinen OH, Tauriainen S, Korpela S, Lappalainen M, Vuorinen T, Haapala AM, Veijola R, Simell O, Ilonen J, Knip M, Hyöty H. Honkanen H, et al. Among authors: laitinen oh. J Clin Virol. 2013 Apr;56(4):348-53. doi: 10.1016/j.jcv.2012.11.018. Epub 2012 Dec 21. J Clin Virol. 2013. PMID: 23261080
Detection of enteroviruses in stools precedes islet autoimmunity by several months: possible evidence for slowly operating mechanisms in virus-induced autoimmunity.
Honkanen H, Oikarinen S, Nurminen N, Laitinen OH, Huhtala H, Lehtonen J, Ruokoranta T, Hankaniemi MM, Lecouturier V, Almond JW, Tauriainen S, Simell O, Ilonen J, Veijola R, Viskari H, Knip M, Hyöty H. Honkanen H, et al. Among authors: laitinen oh. Diabetologia. 2017 Mar;60(3):424-431. doi: 10.1007/s00125-016-4177-z. Epub 2017 Jan 9. Diabetologia. 2017. PMID: 28070615
The abundance of health-associated bacteria is altered in PAH polluted soils-Implications for health in urban areas?
Parajuli A, Grönroos M, Kauppi S, Płociniczak T, Roslund MI, Galitskaya P, Laitinen OH, Hyöty H, Jumpponen A, Strömmer R, Romantschuk M, Hui N, Sinkkonen A. Parajuli A, et al. Among authors: laitinen oh. PLoS One. 2017 Nov 16;12(11):e0187852. doi: 10.1371/journal.pone.0187852. eCollection 2017. PLoS One. 2017. PMID: 29145477 Free PMC article.
Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes.
Sioofy-Khojine AB, Lehtonen J, Nurminen N, Laitinen OH, Oikarinen S, Huhtala H, Pakkanen O, Ruokoranta T, Hankaniemi MM, Toppari J, Vähä-Mäkilä M, Ilonen J, Veijola R, Knip M, Hyöty H. Sioofy-Khojine AB, et al. Among authors: laitinen oh. Diabetologia. 2018 May;61(5):1193-1202. doi: 10.1007/s00125-018-4561-y. Epub 2018 Feb 5. Diabetologia. 2018. PMID: 29404673
Urbanization Reduces Transfer of Diverse Environmental Microbiota Indoors.
Parajuli A, Grönroos M, Siter N, Puhakka R, Vari HK, Roslund MI, Jumpponen A, Nurminen N, Laitinen OH, Hyöty H, Rajaniemi J, Sinkkonen A. Parajuli A, et al. Among authors: laitinen oh. Front Microbiol. 2018 Feb 5;9:84. doi: 10.3389/fmicb.2018.00084. eCollection 2018. Front Microbiol. 2018. PMID: 29467728 Free PMC article.
Nature-derived microbiota exposure as a novel immunomodulatory approach.
Nurminen N, Lin J, Grönroos M, Puhakka R, Kramna L, Vari HK, Viskari H, Oikarinen S, Roslund M, Parajuli A, Tyni I, Cinek O, Laitinen O, Hyöty H, Sinkkonen A. Nurminen N, et al. Future Microbiol. 2018 Jun 1;13:737-744. doi: 10.2217/fmb-2017-0286. Epub 2018 May 17. Future Microbiol. 2018. PMID: 29771153 Clinical Trial.
89 results