Laister R - Search Results

1

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.

Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, West SC, Jasin M, Hakem R. Abraham J, et al. Among authors: laister r. EMBO J. 2003 Nov 17;22(22):6137-47. doi: 10.1093/emboj/cdg580. EMBO J. 2003. PMID: 14609959 Free PMC article.

2

Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?

Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A, Arrowsmith CH. Mark WY, et al. Among authors: laister r. J Mol Biol. 2005 Jan 14;345(2):275-87. doi: 10.1016/j.jmb.2004.10.045. J Mol Biol. 2005. PMID: 15571721

3

A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.

Pineda-Lucena A, Ho CS, Mao DY, Sheng Y, Laister RC, Muhandiram R, Lu Y, Seet BT, Katz S, Szyperski T, Penn LZ, Arrowsmith CH. Pineda-Lucena A, et al. Among authors: laister rc. J Mol Biol. 2005 Aug 5;351(1):182-94. doi: 10.1016/j.jmb.2005.05.046. J Mol Biol. 2005. PMID: 15992821

4

Molecular basis of Pirh2-mediated p53 ubiquitylation.

Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH. Sheng Y, et al. Nat Struct Mol Biol. 2008 Dec;15(12):1334-42. doi: 10.1038/nsmb.1521. Epub 2008 Nov 30. Nat Struct Mol Biol. 2008. PMID: 19043414 Free PMC article.

5

Cruciform structures are a common DNA feature important for regulating biological processes.

Brázda V, Laister RC, Jagelská EB, Arrowsmith C. Brázda V, et al. BMC Mol Biol. 2011 Aug 5;12:33. doi: 10.1186/1471-2199-12-33. BMC Mol Biol. 2011. PMID: 21816114 Free PMC article. Review.

6

The SMX DNA Repair Tri-nuclease.

Wyatt HD, Laister RC, Martin SR, Arrowsmith CH, West SC. Wyatt HD, et al. Among authors: laister rc. Mol Cell. 2017 Mar 2;65(5):848-860.e11. doi: 10.1016/j.molcel.2017.01.031. Mol Cell. 2017. PMID: 28257701 Free PMC article.

7

Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.

Koulov AV, LaPointe P, Lu B, Razvi A, Coppinger J, Dong MQ, Matteson J, Laister R, Arrowsmith C, Yates JR 3rd, Balch WE. Koulov AV, et al. Among authors: laister r. Mol Biol Cell. 2010 Mar 15;21(6):871-84. doi: 10.1091/mbc.e09-12-1017. Epub 2010 Jan 20. Mol Biol Cell. 2010. PMID: 20089831 Free PMC article.

8

Early steps in oxidation-induced SOD1 misfolding: implications for non-amyloid protein aggregation in familial ALS.

Mulligan VK, Kerman A, Laister RC, Sharda PR, Arslan PE, Chakrabartty A. Mulligan VK, et al. J Mol Biol. 2012 Aug 24;421(4-5):631-52. doi: 10.1016/j.jmb.2012.04.016. Epub 2012 Apr 24. J Mol Biol. 2012. PMID: 22542526

9

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.

Sriskanthadevan S, Jeyaraju DV, Chung TE, Prabha S, Xu W, Skrtic M, Jhas B, Hurren R, Gronda M, Wang X, Jitkova Y, Sukhai MA, Lin FH, Maclean N, Laister R, Goard CA, Mullen PJ, Xie S, Penn LZ, Rogers IM, Dick JE, Minden MD, Schimmer AD. Sriskanthadevan S, et al. Among authors: laister r. Blood. 2015 Mar 26;125(13):2120-30. doi: 10.1182/blood-2014-08-594408. Epub 2015 Jan 28. Blood. 2015. PMID: 25631767 Free PMC article.

10

Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity.

Page BD, Khoury H, Laister RC, Fletcher S, Vellozo M, Manzoli A, Yue P, Turkson J, Minden MD, Gunning PT. Page BD, et al. J Med Chem. 2012 Feb 9;55(3):1047-55. doi: 10.1021/jm200720n. Epub 2012 Jan 13. J Med Chem. 2012. PMID: 22148584

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