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The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth.
Dong L, Chen C, Zhang Y, Guo P, Wang Z, Li J, Liu Y, Liu J, Chang R, Li Y, Liang G, Lai W, Sun M, Dougherty U, Bissonnette MB, Wang H, Shen L, Xu MM, Han D. Dong L, et al. Among authors: lai w. Cancer Cell. 2021 Jul 12;39(7):945-957.e10. doi: 10.1016/j.ccell.2021.04.016. Epub 2021 May 20. Cancer Cell. 2021. PMID: 34019807 Free article.
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, Yang Y, Jin KX, Zhao X, Li Y, Ping XL, Lai WY, Wu LG, Jiang G, Wang HL, Sang L, Wang XJ, Yang YG, Zhou Q. Chen T, et al. Among authors: lai wy. Cell Stem Cell. 2015 Mar 5;16(3):289-301. doi: 10.1016/j.stem.2015.01.016. Epub 2015 Feb 12. Cell Stem Cell. 2015. PMID: 25683224 Free article.
Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, Jiang GB, Wang HL, Zhou Q, Wang XJ, Zhao YL, Yang YG. Xiao W, et al. Among authors: lai wy. Mol Cell. 2016 Feb 18;61(4):507-519. doi: 10.1016/j.molcel.2016.01.012. Epub 2016 Feb 11. Mol Cell. 2016. PMID: 26876937 Free article.
5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m5C reader.
Yang X, Yang Y, Sun BF, Chen YS, Xu JW, Lai WY, Li A, Wang X, Bhattarai DP, Xiao W, Sun HY, Zhu Q, Ma HL, Adhikari S, Sun M, Hao YJ, Zhang B, Huang CM, Huang N, Jiang GB, Zhao YL, Wang HL, Sun YP, Yang YG. Yang X, et al. Among authors: lai wy. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18. Cell Res. 2017. PMID: 28418038 Free PMC article.
METTL3-mediated m6A modification is required for cerebellar development.
Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ, Yang YG, Zhou Q. Wang CX, et al. Among authors: lai wy. PLoS Biol. 2018 Jun 7;16(6):e2004880. doi: 10.1371/journal.pbio.2004880. eCollection 2018 Jun. PLoS Biol. 2018. PMID: 29879109 Free PMC article.
UHPLC-Q-TOF/MS detection of UV-induced TpT dimeric lesions in genomic DNA.
Wu D, Lai W, Lyu C, Hang H, Wang H. Wu D, et al. Among authors: lai w. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Oct 1;1096:135-142. doi: 10.1016/j.jchromb.2018.08.015. Epub 2018 Aug 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 30170291
4,137 results