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A plant-derived TRPV3 inhibitor suppresses pain and itch.
Han Y, Luo A, Kamau PM, Takomthong P, Hu J, Boonyarat C, Luo L, Lai R. Han Y, et al. Among authors: lai r. Br J Pharmacol. 2021 Apr;178(7):1669-1683. doi: 10.1111/bph.15390. Epub 2021 Feb 26. Br J Pharmacol. 2021. PMID: 33501656 Free article.
Scorpion Toxin, BmP01, Induces Pain by Targeting TRPV1 Channel.
Hakim MA, Jiang W, Luo L, Li B, Yang S, Song Y, Lai R. Hakim MA, et al. Among authors: lai r. Toxins (Basel). 2015 Sep 14;7(9):3671-87. doi: 10.3390/toxins7093671. Toxins (Basel). 2015. PMID: 26389953 Free PMC article.
Centipedes subdue giant prey by blocking KCNQ channels.
Luo L, Li B, Wang S, Wu F, Wang X, Liang P, Ombati R, Chen J, Lu X, Cui J, Lu Q, Zhang L, Zhou M, Tian C, Yang S, Lai R. Luo L, et al. Among authors: lai r. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1646-1651. doi: 10.1073/pnas.1714760115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358396 Free PMC article.
Molecular mechanism of the tree shrew's insensitivity to spiciness.
Han Y, Li B, Yin TT, Xu C, Ombati R, Luo L, Xia Y, Xu L, Zheng J, Zhang Y, Yang F, Wang GD, Yang S, Lai R. Han Y, et al. Among authors: lai r. PLoS Biol. 2018 Jul 12;16(7):e2004921. doi: 10.1371/journal.pbio.2004921. eCollection 2018 Jul. PLoS Biol. 2018. PMID: 30001322 Free PMC article.
1,836 results