Lai JR - Search Results

1

Protocadherin-1 is essential for cell entry by New World hantaviruses.

Jangra RK, Herbert AS, Li R, Jae LT, Kleinfelter LM, Slough MM, Barker SL, Guardado-Calvo P, Román-Sosa G, Dieterle ME, Kuehne AI, Muena NA, Wirchnianski AS, Nyakatura EK, Fels JM, Ng M, Mittler E, Pan J, Bharrhan S, Wec AZ, Lai JR, Sidhu SS, Tischler ND, Rey FA, Moffat J, Brummelkamp TR, Wang Z, Dye JM, Chandran K. Jangra RK, et al. Among authors: lai jr. Nature. 2018 Nov;563(7732):559-563. doi: 10.1038/s41586-018-0702-1. Epub 2018 Nov 21. Nature. 2018. PMID: 30464266 Free PMC article.

2

Inhibition of Ebola virus entry by a C-peptide targeted to endosomes.

Miller EH, Harrison JS, Radoshitzky SR, Higgins CD, Chi X, Dong L, Kuhn JH, Bavari S, Lai JR, Chandran K. Miller EH, et al. Among authors: lai jr. J Biol Chem. 2011 May 6;286(18):15854-61. doi: 10.1074/jbc.M110.207084. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454542 Free PMC article.

3

Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: stability and pH effects.

Harrison JS, Higgins CD, Chandran K, Lai JR. Harrison JS, et al. Among authors: lai jr. Protein Sci. 2011 Sep;20(9):1587-96. doi: 10.1002/pro.688. Epub 2011 Aug 3. Protein Sci. 2011. PMID: 21739501 Free PMC article.

4

Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle.

Harrison JS, Koellhoffer JF, Chandran K, Lai JR. Harrison JS, et al. Among authors: lai jr. Biochemistry. 2012 Mar 27;51(12):2515-25. doi: 10.1021/bi3000353. Epub 2012 Mar 12. Biochemistry. 2012. PMID: 22369502 Free PMC article.

5

Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation.

Koellhoffer JF, Malashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR. Koellhoffer JF, et al. Among authors: lai jr. Biochemistry. 2012 Oct 2;51(39):7665-75. doi: 10.1021/bi300976m. Epub 2012 Sep 19. Biochemistry. 2012. PMID: 22935026 Free PMC article.

6

Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein.

Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR. Koellhoffer JF, et al. Among authors: lai jr. Chembiochem. 2012 Nov 26;13(17):2549-57. doi: 10.1002/cbic.201200493. Epub 2012 Oct 30. Chembiochem. 2012. PMID: 23111988 Free PMC article.

7

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids.

Regula LK, Harris R, Wang F, Higgins CD, Koellhoffer JF, Zhao Y, Chandran K, Gao J, Girvin ME, Lai JR. Regula LK, et al. Among authors: lai jr. Biochemistry. 2013 May 21;52(20):3393-404. doi: 10.1021/bi400040v. Epub 2013 May 7. Biochemistry. 2013. PMID: 23650881 Free PMC article.

8

C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking.

Higgins CD, Koellhoffer JF, Chandran K, Lai JR. Higgins CD, et al. Among authors: lai jr. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5356-60. doi: 10.1016/j.bmcl.2013.07.056. Epub 2013 Aug 2. Bioorg Med Chem Lett. 2013. PMID: 23962564 Free PMC article.

9

Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge.

Chen G, Koellhoffer JF, Zak SE, Frei JC, Liu N, Long H, Ye W, Nagar K, Pan G, Chandran K, Dye JM, Sidhu SS, Lai JR. Chen G, et al. Among authors: lai jr. ACS Chem Biol. 2014 Oct 17;9(10):2263-73. doi: 10.1021/cb5006454. Epub 2014 Aug 26. ACS Chem Biol. 2014. PMID: 25140871 Free PMC article.

10

Chemical and Structural Aspects of Ebola Virus Entry Inhibitors.

Nyakatura EK, Frei JC, Lai JR. Nyakatura EK, et al. Among authors: lai jr. ACS Infect Dis. 2015 Jan 9;1(1):42-52. doi: 10.1021/id500025n. Epub 2014 Dec 18. ACS Infect Dis. 2015. PMID: 25984565 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

88 results

Search Page