Lai JH - Search Results

1

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.

Roediger B, Lee Q, Tikoo S, Cobbin JCA, Henderson JM, Jormakka M, O'Rourke MB, Padula MP, Pinello N, Henry M, Wynne M, Santagostino SF, Brayton CF, Rasmussen L, Lisowski L, Tay SS, Harris DC, Bertram JF, Dowling JP, Bertolino P, Lai JH, Wu W, Bachovchin WW, Wong JJ, Gorrell MD, Shaban B, Holmes EC, Jolly CJ, Monette S, Weninger W. Roediger B, et al. Among authors: lai jh. Cell. 2018 Oct 4;175(2):530-543.e24. doi: 10.1016/j.cell.2018.08.013. Epub 2018 Sep 13. Cell. 2018. PMID: 30220458 Free PMC article.

2

Microscopic acid-base equilibra of alanyl-boroAlanine.

Lai JH, Zhou Y, Sudmeier JL, Wu W, Sanford DG, Hliang M, Poplawski S, Bachovchin WW. Lai JH, et al. Adv Exp Med Biol. 2003;524:333-8. doi: 10.1007/0-306-47920-6_39. Adv Exp Med Biol. 2003. PMID: 12675255 No abstract available.

3

Autochelation in dipeptide boronic acids: pH-dependent structures and equilibria of Asp-boroPro and His-boroPro by NMR spectroscopy.

Sudmeier JL, Zhou Y, Lai JH, Maw HH, Wu W, Bachovchin WW. Sudmeier JL, et al. Among authors: lai jh. J Am Chem Soc. 2005 Jun 8;127(22):8112-9. doi: 10.1021/ja050215e. J Am Chem Soc. 2005. PMID: 15926838

4

Synthesis and structural investigation of internally coordinated alpha-amidoboronic acids.

Lai JH, Liu Y, Wu W, Zhou Y, Maw HH, Bachovchin WW, Bhat KL, Bock CW. Lai JH, et al. J Org Chem. 2006 Jan 20;71(2):512-9. doi: 10.1021/jo051757h. J Org Chem. 2006. PMID: 16408958

5

Synthesis and characterization of constrained peptidomimetic dipeptidyl peptidase IV inhibitors: amino-lactam boroalanines.

Lai JH, Wu W, Zhou Y, Maw HH, Liu Y, Milo LJ Jr, Poplawski SE, Henry GD, Sudmeier JL, Sanford DG, Bachovchin WW. Lai JH, et al. J Med Chem. 2007 May 17;50(10):2391-8. doi: 10.1021/jm061321+. Epub 2007 Apr 26. J Med Chem. 2007. PMID: 17458948

6

Dipeptide boronic acid inhibitors of dipeptidyl peptidase IV: determinants of potency and in vivo efficacy and safety.

Connolly BA, Sanford DG, Chiluwal AK, Healey SE, Peters DE, Dimare MT, Wu W, Liu Y, Maw H, Zhou Y, Li Y, Jin Z, Sudmeier JL, Lai JH, Bachovchin WW. Connolly BA, et al. Among authors: lai jh. J Med Chem. 2008 Oct 9;51(19):6005-13. doi: 10.1021/jm800390n. Epub 2008 Sep 11. J Med Chem. 2008. PMID: 18783201

7

Pro-soft Val-boroPro: a strategy for enhancing in vivo performance of boronic acid inhibitors of serine proteases.

Poplawski SE, Lai JH, Sanford DG, Sudmeier JL, Wu W, Bachovchin WW. Poplawski SE, et al. Among authors: lai jh. J Med Chem. 2011 Apr 14;54(7):2022-8. doi: 10.1021/jm100972f. Epub 2011 Mar 9. J Med Chem. 2011. PMID: 21388136

8

Chemical and biological evaluation of dipeptidyl boronic acid proteasome inhibitors for use in prodrugs and pro-soft drugs targeting solid tumors.

Milo LJ Jr, Lai JH, Wu W, Liu Y, Maw H, Li Y, Jin Z, Shu Y, Poplawski SE, Wu Y, Sanford DG, Sudmeier JL, Bachovchin WW. Milo LJ Jr, et al. Among authors: lai jh. J Med Chem. 2011 Jul 14;54(13):4365-77. doi: 10.1021/jm200460q. Epub 2011 Jun 20. J Med Chem. 2011. PMID: 21634429

9

4-Substituted boro-proline dipeptides: synthesis, characterization, and dipeptidyl peptidase IV, 8, and 9 activities.

Wu W, Liu Y, Milo LJ Jr, Shu Y, Zhao P, Li Y, Woznica I, Yu G, Sanford DG, Zhou Y, Poplawski SE, Connolly BA, Sudmeier JL, Bachovchin WW, Lai JH. Wu W, et al. Among authors: lai jh. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5536-40. doi: 10.1016/j.bmcl.2012.07.033. Epub 2012 Jul 14. Bioorg Med Chem Lett. 2012. PMID: 22853995

10

Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.

Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG, Bachovchin WW. Poplawski SE, et al. Among authors: lai jh. J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a. Epub 2013 Apr 29. J Med Chem. 2013. PMID: 23594271 Free PMC article.

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