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Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1, PX-2, NNL-1, and Their Analogues.
Markham J, Sparkes E, Boyd R, Chen S, Manning JJ, Finlay D, Lai F, McGregor E, Maloney CJ, Gerona RR, Connor M, McGregor IS, Hibbs DE, Glass M, Kevin RC, Banister SD. Markham J, et al. Among authors: lai f. ACS Chem Neurosci. 2022 Apr 20;13(8):1281-1295. doi: 10.1021/acschemneuro.2c00034. Epub 2022 Apr 11. ACS Chem Neurosci. 2022. PMID: 35404067
Identification of dual PPARα/γ agonists and their effects on lipid metabolism.
Gao Q, Hanh J, Váradi L, Cairns R, Sjöström H, Liao VW, Wood P, Balaban S, Ong JA, Lin HY, Lai F, Hoy AJ, Grewal T, Groundwater PW, Hibbs DE. Gao Q, et al. Among authors: lai f. Bioorg Med Chem. 2015 Dec 15;23(24):7676-84. doi: 10.1016/j.bmc.2015.11.013. Epub 2015 Nov 14. Bioorg Med Chem. 2015. PMID: 26616289
cyp51A Mutations, Extrolite Profiles, and Antifungal Susceptibility in Clinical and Environmental Isolates of the Aspergillus viridinutans Species Complex.
Talbot JJ, Frisvad JC, Meis JF, Hagen F, Verweij PE, Hibbs DE, Lai F, Groundwater PW, Samson RA, Kidd SE, Barrs VR, Houbraken J. Talbot JJ, et al. Among authors: lai f. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00632-19. doi: 10.1128/AAC.00632-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451501 Free PMC article.
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?
Ametovski A, Cairns EA, Grafinger KE, Cannaert A, Deventer MH, Chen S, Wu X, Shepperson CE, Lai F, Ellison R, Gerona R, Blakey K, Kevin R, McGregor IS, Hibbs DE, Glass M, Stove C, Auwärter V, Banister SD. Ametovski A, et al. Among authors: lai f. ACS Chem Neurosci. 2021 Nov 3;12(21):4020-4036. doi: 10.1021/acschemneuro.1c00348. Epub 2021 Oct 22. ACS Chem Neurosci. 2021. PMID: 34676751
Structure-activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA.
Sparkes E, Cairns EA, Kevin RC, Lai F, Grafinger KE, Chen S, Deventer MH, Ellison R, Boyd R, Martin LJ, McGregor IS, Gerona RR, Hibbs DE, Auwärter V, Glass M, Stove C, Banister SD. Sparkes E, et al. Among authors: lai f. RSC Med Chem. 2021 Oct 25;13(2):156-174. doi: 10.1039/d1md00242b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308023 Free PMC article.
Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors.
Kevin RC, Mirlohi S, Manning JJ, Boyd R, Cairns EA, Ametovski A, Lai F, Luo JL, Jorgensen W, Ellison R, Gerona RR, Hibbs DE, McGregor IS, Glass M, Connor M, Bladen C, Zamponi GW, Banister SD. Kevin RC, et al. Among authors: lai f. ACS Chem Neurosci. 2022 May 4;13(9):1395-1409. doi: 10.1021/acschemneuro.1c00822. Epub 2022 Apr 20. ACS Chem Neurosci. 2022. PMID: 35442021
1,946 results