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Reducing protein oxidation reverses lung fibrosis.
Anathy V, Lahue KG, Chapman DG, Chia SB, Casey DT, Aboushousha R, van der Velden JLJ, Elko E, Hoffman SM, McMillan DH, Jones JT, Nolin JD, Abdalla S, Schneider R, Seward DJ, Roberson EC, Liptak MD, Cousins ME, Butnor KJ, Taatjes DJ, Budd RC, Irvin CG, Ho YS, Hakem R, Brown KK, Matsui R, Bachschmid MM, Gomez JL, Kaminski N, van der Vliet A, Janssen-Heininger YMW. Anathy V, et al. Among authors: lahue kg. Nat Med. 2018 Aug;24(8):1128-1135. doi: 10.1038/s41591-018-0090-y. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988126 Free PMC article.
Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease.
Hoffman SM, Tully JE, Lahue KG, Anathy V, Nolin JD, Guala AS, van der Velden JL, Ho YS, Aliyeva M, Daphtary N, Lundblad LK, Irvin CG, Janssen-Heininger YM. Hoffman SM, et al. Among authors: lahue kg. Am J Physiol Lung Cell Mol Physiol. 2012 Sep 15;303(6):L528-38. doi: 10.1152/ajplung.00167.2012. Epub 2012 Jun 29. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22752969 Free PMC article.
Emerging mechanisms of glutathione-dependent chemistry in biology and disease.
Janssen-Heininger YM, Nolin JD, Hoffman SM, van der Velden JL, Tully JE, Lahue KG, Abdalla ST, Chapman DG, Reynaert NL, van der Vliet A, Anathy V. Janssen-Heininger YM, et al. Among authors: lahue kg. J Cell Biochem. 2013 Sep;114(9):1962-8. doi: 10.1002/jcb.24551. J Cell Biochem. 2013. PMID: 23554102 Free PMC article. Review.
Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation.
van der Velden JL, Hoffman SM, Alcorn JF, Tully JE, Chapman DG, Lahue KG, Guala AS, Lundblad LK, Aliyeva M, Daphtary N, Irvin CG, Janssen-Heininger YM. van der Velden JL, et al. Among authors: lahue kg. Am J Physiol Lung Cell Mol Physiol. 2014 May 1;306(9):L866-75. doi: 10.1152/ajplung.00153.2013. Epub 2014 Mar 7. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24610935 Free PMC article.
Protein disulfide isomerase-endoplasmic reticulum resident protein 57 regulates allergen-induced airways inflammation, fibrosis, and hyperresponsiveness.
Hoffman SM, Chapman DG, Lahue KG, Cahoon JM, Rattu GK, Daphtary N, Aliyeva M, Fortner KA, Erzurum SC, Comhair SA, Woodruff PG, Bhakta N, Dixon AE, Irvin CG, Janssen-Heininger YM, Poynter ME, Anathy V. Hoffman SM, et al. Among authors: lahue kg. J Allergy Clin Immunol. 2016 Mar;137(3):822-32.e7. doi: 10.1016/j.jaci.2015.08.018. Epub 2015 Oct 4. J Allergy Clin Immunol. 2016. PMID: 26435004 Free PMC article.
29 results