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The secretome of stressed peripheral blood mononuclear cells increases tissue survival in a rodent epigastric flap model.
Hacker S, Mittermayr R, Traxler D, Keibl C, Resch A, Salminger S, Leiss H, Hacker P, Gabriel C, Golabi B, Pauzenberger R, Slezak P, Laggner M, Mildner M, Michlits W, Ankersmit HJ. Hacker S, et al. Among authors: laggner m. Bioeng Transl Med. 2020 Sep 22;6(1):e10186. doi: 10.1002/btm2.10186. eCollection 2021 Jan. Bioeng Transl Med. 2020. PMID: 33532586 Free PMC article.
Different pro-angiogenic potential of γ-irradiated PBMC-derived secretome and its subfractions.
Wagner T, Traxler D, Simader E, Beer L, Narzt MS, Gruber F, Madlener S, Laggner M, Erb M, Vorstandlechner V, Gugerell A, Radtke C, Gnecchi M, Peterbauer A, Gschwandtner M, Tschachler E, Keibl C, Slezak P, Ankersmit HJ, Mildner M. Wagner T, et al. Among authors: laggner m. Sci Rep. 2018 Dec 20;8(1):18016. doi: 10.1038/s41598-018-36928-6. Sci Rep. 2018. PMID: 30573762 Free PMC article.
Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease.
Wuschko S, Gugerell A, Chabicovsky M, Hofbauer H, Laggner M, Erb M, Ostler T, Peterbauer A, Suessner S, Demyanets S, Leuschner J, Moser B, Mildner M, Ankersmit HJ. Wuschko S, et al. Among authors: laggner m. Sci Rep. 2019 Apr 3;9(1):5598. doi: 10.1038/s41598-019-42057-5. Sci Rep. 2019. PMID: 30944367 Free PMC article.
The Differentiation-Associated Keratinocyte Protein Cornifelin Contributes to Cell-Cell Adhesion of Epidermal and Mucosal Keratinocytes.
Wagner T, Beer L, Gschwandtner M, Eckhart L, Kalinina P, Laggner M, Ellinger A, Gruber R, Kuchler U, Golabi B, Tschachler E, Mildner M. Wagner T, et al. Among authors: laggner m. J Invest Dermatol. 2019 Nov;139(11):2292-2301.e9. doi: 10.1016/j.jid.2019.04.019. Epub 2019 May 24. J Invest Dermatol. 2019. PMID: 31129056 Free article.
Tissue-regenerative potential of the secretome of γ-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis.
Simader E, Beer L, Laggner M, Vorstandlechner V, Gugerell A, Erb M, Kalinina P, Copic D, Moser D, Spittler A, Tschachler E, Jan Ankersmit H, Mildner M. Simader E, et al. Among authors: laggner m. Cell Death Dis. 2019 Sep 30;10(10):729. doi: 10.1038/s41419-019-1974-6. Cell Death Dis. 2019. PMID: 31570701 Free PMC article.
Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products.
Laggner M, Gugerell A, Bachmann C, Hofbauer H, Vorstandlechner V, Seibold M, Gouya Lechner G, Peterbauer A, Madlener S, Demyanets S, Sorgenfrey D, Ostler T, Erb M, Mildner M, Ankersmit HJ. Laggner M, et al. Stem Cell Res Ther. 2020 Jan 3;11(1):9. doi: 10.1186/s13287-019-1524-2. Stem Cell Res Ther. 2020. PMID: 31900195 Free PMC article.
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