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Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity.
Berglund E, Maaskola J, Schultz N, Friedrich S, Marklund M, Bergenstråhle J, Tarish F, Tanoglidi A, Vickovic S, Larsson L, Salmén F, Ogris C, Wallenborg K, Lagergren J, Ståhl P, Sonnhammer E, Helleday T, Lundeberg J. Berglund E, et al. Among authors: lagergren j. Nat Commun. 2018 Jun 20;9(1):2419. doi: 10.1038/s41467-018-04724-5. Nat Commun. 2018. PMID: 29925878 Free PMC article.
Inferring tumor progression in large datasets.
Mohaghegh Neyshabouri M, Jun SH, Lagergren J. Mohaghegh Neyshabouri M, et al. Among authors: lagergren j. PLoS Comput Biol. 2020 Oct 9;16(10):e1008183. doi: 10.1371/journal.pcbi.1008183. eCollection 2020 Oct. PLoS Comput Biol. 2020. PMID: 33035204 Free PMC article.
Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction.
Chen X, Sifakis EG, Robertson S, Neo SY, Jun SH, Tong L, Hui Min AT, Lövrot J, Hellgren R, Margolin S, Bergh J, Foukakis T, Lagergren J, Lundqvist A, Ma R, Hartman J. Chen X, et al. Among authors: lagergren j. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2209856120. doi: 10.1073/pnas.2209856120. Epub 2022 Dec 27. Proc Natl Acad Sci U S A. 2023. PMID: 36574653 Free PMC article.
Spatial transcriptomics of B cell and T cell receptors reveals lymphocyte clonal dynamics.
Engblom C, Thrane K, Lin Q, Andersson A, Toosi H, Chen X, Steiner E, Lu C, Mantovani G, Hagemann-Jensen M, Saarenpää S, Jangard M, Saez-Rodriguez J, Michaëlsson J, Hartman J, Lagergren J, Mold JE, Lundeberg J, Frisén J. Engblom C, et al. Among authors: lagergren j. Science. 2023 Dec 8;382(6675):eadf8486. doi: 10.1126/science.adf8486. Epub 2023 Dec 8. Science. 2023. PMID: 38060664
ToMExO: A probabilistic tree-structured model for cancer progression.
Mohaghegh Neyshabouri M, Lagergren J. Mohaghegh Neyshabouri M, et al. Among authors: lagergren j. PLoS Comput Biol. 2022 Dec 5;18(12):e1010732. doi: 10.1371/journal.pcbi.1010732. eCollection 2022 Dec. PLoS Comput Biol. 2022. PMID: 36469540 Free PMC article.
Species Tree Inference Using a Mixture Model.
Ullah I, Parviainen P, Lagergren J. Ullah I, et al. Among authors: lagergren j. Mol Biol Evol. 2015 Sep;32(9):2469-82. doi: 10.1093/molbev/msv115. Epub 2015 May 11. Mol Biol Evol. 2015. PMID: 25963975
In the second phase, PrIME-DLRS, a method based on the DLRS model (Akerborg O, Sennblad B, Arvestad L, Lagergren J. 2009. Simultaneous Bayesian gene tree reconstruction and reconciliation analysis. ...PrIME-DLRS can handle multicopy gene families since DLRS, apart f …
In the second phase, PrIME-DLRS, a method based on the DLRS model (Akerborg O, Sennblad B, Arvestad L, Lagergren J. 2009. Simu …
668 results