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Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties.
Herrera-Arozamena C, Estrada-Valencia M, Pérez C, Lagartera L, Morales-García JA, Pérez-Castillo A, Franco-Gonzalez JF, Michalska P, Duarte P, León R, López MG, Mills A, Gago F, García-Yagüe ÁJ, Fernández-Ginés R, Cuadrado A, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: lagartera l. Eur J Med Chem. 2020 Mar 15;190:112090. doi: 10.1016/j.ejmech.2020.112090. Epub 2020 Jan 25. Eur J Med Chem. 2020. PMID: 32018096 Free article.
Chromenopyrazole, a Versatile Cannabinoid Scaffold with in Vivo Activity in a Model of Multiple Sclerosis.
Morales P, Gómez-Cañas M, Navarro G, Hurst DP, Carrillo-Salinas FJ, Lagartera L, Pazos R, Goya P, Reggio PH, Guaza C, Franco R, Fernández-Ruiz J, Jagerovic N. Morales P, et al. Among authors: lagartera l. J Med Chem. 2016 Jul 28;59(14):6753-6771. doi: 10.1021/acs.jmedchem.6b00397. Epub 2016 Jul 6. J Med Chem. 2016. PMID: 27309150 Free PMC article.
Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents.
Peraza DA, Cercós P, Miaja P, Merinero YG, Lagartera L, Socuéllamos PG, Izquierdo García C, Sánchez SA, López-Hurtado A, Martín-Martínez M, Olivos-Oré LA, Naranjo JR, Artalejo AR, Gutiérrez-Rodríguez M, Valenzuela C. Peraza DA, et al. Among authors: lagartera l. Front Mol Neurosci. 2019 Feb 4;12:11. doi: 10.3389/fnmol.2019.00011. eCollection 2019. Front Mol Neurosci. 2019. PMID: 30787866 Free PMC article.
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4.
de Las Rivas M, Paul Daniel EJ, Coelho H, Lira-Navarrete E, Raich L, Compañón I, Diniz A, Lagartera L, Jiménez-Barbero J, Clausen H, Rovira C, Marcelo F, Corzana F, Gerken TA, Hurtado-Guerrero R. de Las Rivas M, et al. Among authors: lagartera l. ACS Cent Sci. 2018 Sep 26;4(9):1274-1290. doi: 10.1021/acscentsci.8b00488. Epub 2018 Sep 14. ACS Cent Sci. 2018. PMID: 30276263 Free PMC article.
Functional and structural analysis of AT-specific minor groove binders that disrupt DNA-protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast.
Millan CR, Acosta-Reyes FJ, Lagartera L, Ebiloma GU, Lemgruber L, Nué Martínez JJ, Saperas N, Dardonville C, de Koning HP, Campos JL. Millan CR, et al. Among authors: lagartera l. Nucleic Acids Res. 2017 Aug 21;45(14):8378-8391. doi: 10.1093/nar/gkx521. Nucleic Acids Res. 2017. PMID: 28637278 Free PMC article.
The structure and flexibility analysis of the Arabidopsis synaptotagmin 1 reveal the basis of its regulation at membrane contact sites.
Benavente JL, Siliqi D, Infantes L, Lagartera L, Mills A, Gago F, Ruiz-López N, Botella MA, Sánchez-Barrena MJ, Albert A. Benavente JL, et al. Among authors: lagartera l. Life Sci Alliance. 2021 Aug 18;4(10):e202101152. doi: 10.26508/lsa.202101152. Print 2021 Oct. Life Sci Alliance. 2021. PMID: 34408000 Free PMC article.
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