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963 results

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Discovery of a first-in-class EZH2 selective degrader.
Ma A, Stratikopoulos E, Park KS, Wei J, Martin TC, Yang X, Schwarz M, Leshchenko V, Rialdi A, Dale B, Lagana A, Guccione E, Parekh S, Parsons R, Jin J. Ma A, et al. Among authors: lagana a. Nat Chem Biol. 2020 Feb;16(2):214-222. doi: 10.1038/s41589-019-0421-4. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819273 Free PMC article.
A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma.
Chari A, Cho HJ, Dhadwal A, Morgan G, La L, Zarychta K, Catamero D, Florendo E, Stevens N, Verina D, Chan E, Leshchenko V, Laganà A, Perumal D, Mei AH, Tung K, Fukui J, Jagannath S, Parekh S. Chari A, et al. Among authors: lagana a. Blood Adv. 2017 Aug 21;1(19):1575-1583. doi: 10.1182/bloodadvances.2017007427. eCollection 2017 Aug 22. Blood Adv. 2017. PMID: 29296798 Free PMC article.
A Network Analysis of Multiple Myeloma Related Gene Signatures.
Liu Y, Yu H, Yoo S, Lee E, Laganà A, Parekh S, Schadt EE, Wang L, Zhu J. Liu Y, et al. Among authors: lagana a. Cancers (Basel). 2019 Sep 27;11(10):1452. doi: 10.3390/cancers11101452. Cancers (Basel). 2019. PMID: 31569720 Free PMC article.
Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma.
Perumal D, Imai N, Laganà A, Finnigan J, Melnekoff D, Leshchenko VV, Solovyov A, Madduri D, Chari A, Cho HJ, Dudley JT, Brody JD, Jagannath S, Greenbaum B, Gnjatic S, Bhardwaj N, Parekh S. Perumal D, et al. Among authors: lagana a. Clin Cancer Res. 2020 Jan 15;26(2):450-464. doi: 10.1158/1078-0432.CCR-19-2309. Epub 2019 Dec 19. Clin Cancer Res. 2020. PMID: 31857430 Free PMC article.
A phase II study of pomalidomide, daily oral cyclophosphamide, and dexamethasone in relapsed/refractory multiple myeloma.
Van Oekelen O, Parekh S, Cho HJ, Vishnuvardhan N, Madduri D, Richter J, Ip C, Lau K, Florendo E, Mancia IS, Thomas J, Verina D, Chan E, Zarychta K, La L, Strumolo G, Melnekoff DT, Leshchenko VV, Kim-Schulze S, Couto S, Wang M, Pierceall WE, Thakurta A, Laganà A, Jagannath S, Chari A. Van Oekelen O, et al. Among authors: lagana a. Leuk Lymphoma. 2020 Sep;61(9):2208-2215. doi: 10.1080/10428194.2020.1805111. Epub 2020 Aug 19. Leuk Lymphoma. 2020. PMID: 32812822 Clinical Trial.
A Critical Role for Fas-Mediated Off-Target Tumor Killing in T-cell Immunotherapy.
Upadhyay R, Boiarsky JA, Pantsulaia G, Svensson-Arvelund J, Lin MJ, Wroblewska A, Bhalla S, Scholler N, Bot A, Rossi JM, Sadek N, Parekh S, Lagana A, Baccarini A, Merad M, Brown BD, Brody JD. Upadhyay R, et al. Among authors: lagana a. Cancer Discov. 2021 Mar;11(3):599-613. doi: 10.1158/2159-8290.CD-20-0756. Epub 2020 Dec 17. Cancer Discov. 2021. PMID: 33334730 Free PMC article.
SOX11 Inhibitors Are Cytotoxic in Mantle Cell Lymphoma.
Jatiani SS, Christie S, Leshchenko VV, Jain R, Kapoor A, Bisignano P, Lee C, Kaniskan HÜ, Edwards D, Meng F, Laganà A, Youssef Y, Wiestner A, Alinari L, Jin J, Filizola M, Aggarwal AK, Parekh S. Jatiani SS, et al. Among authors: lagana a. Clin Cancer Res. 2021 Aug 15;27(16):4652-4663. doi: 10.1158/1078-0432.CCR-20-5039. Epub 2021 Jun 22. Clin Cancer Res. 2021. PMID: 34158358 Free PMC article.
963 results