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Formation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nuclease.
PLoS Genet. 2014 Dec 4;10(12):e1004805. doi: 10.1371/journal.pgen.1004805. eCollection 2014 Dec.
PLoS Genet. 2014.
PMID: 25474106
Free PMC article.
Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism.
Laffitte MC, Leprohon P, Hainse M, Légaré D, Masson JY, Ouellette M.
Laffitte MC, et al.
PLoS Genet. 2016 Jun 17;12(6):e1006117. doi: 10.1371/journal.pgen.1006117. eCollection 2016 Jun.
PLoS Genet. 2016.
PMID: 27314941
Free PMC article.
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Intrachromosomal amplification, locus deletion and point mutation in the aquaglyceroporin AQP1 gene in antimony resistant Leishmania (Viannia) guyanensis.
Monte-Neto R, Laffitte MC, Leprohon P, Reis P, Frézard F, Ouellette M.
Monte-Neto R, et al. Among authors: laffitte mc.
PLoS Negl Trop Dis. 2015 Feb 13;9(2):e0003476. doi: 10.1371/journal.pntd.0003476. eCollection 2015 Feb.
PLoS Negl Trop Dis. 2015.
PMID: 25679388
Free PMC article.
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Deep-sequencing revealing mutation dynamics in the miltefosine transporter gene in Leishmania infantum selected for miltefosine resistance.
Laffitte MC, Leprohon P, Légaré D, Ouellette M.
Laffitte MC, et al.
Parasitol Res. 2016 Oct;115(10):3699-703. doi: 10.1007/s00436-016-5195-y. Epub 2016 Jul 26.
Parasitol Res. 2016.
PMID: 27457482
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DNA repair pathways in trypanosomatids: from DNA repair to drug resistance.
Genois MM, Paquet ER, Laffitte MC, Maity R, Rodrigue A, Ouellette M, Masson JY.
Genois MM, et al. Among authors: laffitte mc.
Microbiol Mol Biol Rev. 2014 Mar;78(1):40-73. doi: 10.1128/MMBR.00045-13.
Microbiol Mol Biol Rev. 2014.
PMID: 24600040
Free PMC article.
Review.
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Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum.
Brancucci NMB, Gerdt JP, Wang C, De Niz M, Philip N, Adapa SR, Zhang M, Hitz E, Niederwieser I, Boltryk SD, Laffitte MC, Clark MA, Grüring C, Ravel D, Blancke Soares A, Demas A, Bopp S, Rubio-Ruiz B, Conejo-Garcia A, Wirth DF, Gendaszewska-Darmach E, Duraisingh MT, Adams JH, Voss TS, Waters AP, Jiang RHY, Clardy J, Marti M.
Brancucci NMB, et al. Among authors: laffitte mc.
Cell. 2017 Dec 14;171(7):1532-1544.e15. doi: 10.1016/j.cell.2017.10.020. Epub 2017 Nov 9.
Cell. 2017.
PMID: 29129376
Free PMC article.
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Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance.
Laffitte MN, Leprohon P, Papadopoulou B, Ouellette M.
Laffitte MN, et al.
F1000Res. 2016 Sep 20;5:2350. doi: 10.12688/f1000research.9218.1. eCollection 2016.
F1000Res. 2016.
PMID: 27703673
Free PMC article.
Review.
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