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USP7 limits CDK1 activity throughout the cell cycle.
Galarreta A, Valledor P, Ubieto-Capella P, Lafarga V, Zarzuela E, Muñoz J, Malumbres M, Lecona E, Fernandez-Capetillo O. Galarreta A, et al. Among authors: lafarga v. EMBO J. 2021 Jun 1;40(11):e99692. doi: 10.15252/embj.201899692. Epub 2021 Apr 15. EMBO J. 2021. PMID: 33856059 Free PMC article.
Efficacy of ATR inhibitors as single agents in Ewing sarcoma.
Nieto-Soler M, Morgado-Palacin I, Lafarga V, Lecona E, Murga M, Callen E, Azorin D, Alonso J, Lopez-Contreras AJ, Nussenzweig A, Fernandez-Capetillo O. Nieto-Soler M, et al. Among authors: lafarga v. Oncotarget. 2016 Sep 13;7(37):58759-58767. doi: 10.18632/oncotarget.11643. Oncotarget. 2016. PMID: 27577084 Free PMC article.
Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.
Morgado-Palacin I, Day A, Murga M, Lafarga V, Anton ME, Tubbs A, Chen HT, Ergan A, Anderson R, Bhandoola A, Pike KG, Barlaam B, Cadogan E, Wang X, Pierce AJ, Hubbard C, Armstrong SA, Nussenzweig A, Fernandez-Capetillo O. Morgado-Palacin I, et al. Among authors: lafarga v. Sci Signal. 2016 Sep 13;9(445):ra91. doi: 10.1126/scisignal.aad8243. Sci Signal. 2016. PMID: 27625305 Free PMC article.
USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.
Franz A, Valledor P, Ubieto-Capella P, Pilger D, Galarreta A, Lafarga V, Fernández-Llorente A, de la Vega-Barranco G, den Brave F, Hoppe T, Fernandez-Capetillo O, Lecona E. Franz A, et al. Among authors: lafarga v. Cell Rep. 2021 Oct 12;37(2):109819. doi: 10.1016/j.celrep.2021.109819. Cell Rep. 2021. PMID: 34644576 Free PMC article.
34 results