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Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A. Pecnard S, et al. Among authors: lafanechere l. Eur J Med Chem. 2021 Jan 1;209:112873. doi: 10.1016/j.ejmech.2020.112873. Epub 2020 Oct 4. Eur J Med Chem. 2021. PMID: 33038796
A New Quantitative Cell-Based Assay Reveals Unexpected Microtubule Stabilizing Activity of Certain Kinase Inhibitors, Clinically Approved or in the Process of Approval.
Ramirez-Rios S, Michallet S, Peris L, Barette C, Rabat C, Feng Y, Fauvarque MO, Andrieux A, Sadoul K, Lafanechère L. Ramirez-Rios S, et al. Among authors: lafanechere l. Front Pharmacol. 2020 Apr 30;11:543. doi: 10.3389/fphar.2020.00543. eCollection 2020. Front Pharmacol. 2020. PMID: 32425788 Free PMC article.
Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells.
Peronne L, Denarier E, Rai A, Prudent R, Vernet A, Suzanne P, Ramirez-Rios S, Michallet S, Guidetti M, Vollaire J, Lucena-Agell D, Ribba AS, Josserand V, Coll JL, Dallemagne P, Díaz JF, Oliva MÁ, Sadoul K, Akhmanova A, Andrieux A, Lafanechère L. Peronne L, et al. Among authors: lafanechere l. Cancers (Basel). 2020 Aug 6;12(8):2196. doi: 10.3390/cancers12082196. Cancers (Basel). 2020. PMID: 32781579 Free PMC article.
Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors.
Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A. Hauguel C, et al. Among authors: lafanechere l. Eur J Med Chem. 2022 Oct 5;240:114573. doi: 10.1016/j.ejmech.2022.114573. Epub 2022 Jul 1. Eur J Med Chem. 2022. PMID: 35797900 Free article.
Antitumoral activity of allosteric inhibitors of protein kinase CK2.
Moucadel V, Prudent R, Sautel CF, Teillet F, Barette C, Lafanechere L, Receveur-Brechot V, Cochet C. Moucadel V, et al. Among authors: lafanechere l. Oncotarget. 2011 Dec;2(12):997-1010. doi: 10.18632/oncotarget.361. Oncotarget. 2011. PMID: 22184283 Free PMC article.
Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.
Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, Busser B. Gilson P, et al. Among authors: lafanechere l. Sci Rep. 2017 Aug 31;7(1):10209. doi: 10.1038/s41598-017-09491-9. Sci Rep. 2017. PMID: 28860487 Free PMC article.
The pyrrolopyrimidine colchicine-binding site agent PP-13 reduces the metastatic dissemination of invasive cancer cells in vitro and in vivo.
Gilson P, Couvet M, Vanwonterghem L, Henry M, Vollaire J, Baulin V, Werner M, Orlowska A, Josserand V, Mahuteau-Betzer F, Lafanechère L, Coll JL, Busser B, Hurbin A. Gilson P, et al. Among authors: lafanechere l. Biochem Pharmacol. 2019 Feb;160:1-13. doi: 10.1016/j.bcp.2018.12.004. Epub 2018 Dec 7. Biochem Pharmacol. 2019. PMID: 30529691
74 results