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Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies.
Rossi M, Candelise N, Baiardi S, Capellari S, Giannini G, Orrù CD, Antelmi E, Mammana A, Hughson AG, Calandra-Buonaura G, Ladogana A, Plazzi G, Cortelli P, Caughey B, Parchi P. Rossi M, et al. Among authors: ladogana a. Acta Neuropathol. 2020 Jul;140(1):49-62. doi: 10.1007/s00401-020-02160-8. Epub 2020 Apr 27. Acta Neuropathol. 2020. PMID: 32342188 Free PMC article.
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.
Parchi P, Strammiello R, Notari S, Giese A, Langeveld JP, Ladogana A, Zerr I, Roncaroli F, Cras P, Ghetti B, Pocchiari M, Kretzschmar H, Capellari S. Parchi P, et al. Among authors: ladogana a. Acta Neuropathol. 2009 Nov;118(5):659-71. doi: 10.1007/s00401-009-0585-1. Epub 2009 Aug 29. Acta Neuropathol. 2009. PMID: 19718500 Free PMC article.
Mutant PrPCJD prevails over wild-type PrPCJD in the brain of V210I and R208H genetic Creutzfeldt-Jakob disease patients.
Cardone F, Principe S, Schininà ME, Maras B, Capellari S, Parchi P, Notari S, Di Francesco L, Poleggi A, Galeno R, Vinci R, Mellina V, Almonti S, Ladogana A, Pocchiari M. Cardone F, et al. Among authors: ladogana a. Biochem Biophys Res Commun. 2014 Nov 14;454(2):289-94. doi: 10.1016/j.bbrc.2014.10.051. Epub 2014 Oct 19. Biochem Biophys Res Commun. 2014. PMID: 25450391
Quantifying prion disease penetrance using large population control cohorts.
Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM; Exome Aggregation Consortium (ExAC); Daly MJ, MacArthur DG. Minikel EV, et al. Among authors: ladogana a. Sci Transl Med. 2016 Jan 20;8(322):322ra9. doi: 10.1126/scitranslmed.aad5169. Sci Transl Med. 2016. PMID: 26791950 Free PMC article.
Patient with rapidly evolving neurological disease with neuropathological lesions of Creutzfeldt-Jakob disease, Lewy body dementia, chronic subcortical vascular encephalopathy and meningothelial meningioma.
Vita MG, Tiple D, Bizzarro A, Ladogana A, Colaizzo E, Capellari S, Rossi M, Parchi P, Masullo C, Pocchiari M. Vita MG, et al. Among authors: ladogana a. Neuropathology. 2017 Apr;37(2):110-115. doi: 10.1111/neup.12343. Epub 2016 Sep 16. Neuropathology. 2017. PMID: 27634418
Diagnosis of Human Prion Disease Using Real-Time Quaking-Induced Conversion Testing of Olfactory Mucosa and Cerebrospinal Fluid Samples.
Bongianni M, Orrù C, Groveman BR, Sacchetto L, Fiorini M, Tonoli G, Triva G, Capaldi S, Testi S, Ferrari S, Cagnin A, Ladogana A, Poleggi A, Colaizzo E, Tiple D, Vaianella L, Castriciano S, Marchioni D, Hughson AG, Imperiale D, Cattaruzza T, Fabrizi GM, Pocchiari M, Monaco S, Caughey B, Zanusso G. Bongianni M, et al. Among authors: ladogana a. JAMA Neurol. 2017 Feb 1;74(2):155-162. doi: 10.1001/jamaneurol.2016.4614. JAMA Neurol. 2017. PMID: 27942718
Extended and direct evaluation of RT-QuIC assays for Creutzfeldt-Jakob disease diagnosis.
Groveman BR, Orrú CD, Hughson AG, Bongianni M, Fiorini M, Imperiale D, Ladogana A, Pocchiari M, Zanusso G, Caughey B. Groveman BR, et al. Among authors: ladogana a. Ann Clin Transl Neurol. 2016 Dec 27;4(2):139-144. doi: 10.1002/acn3.378. eCollection 2017 Feb. Ann Clin Transl Neurol. 2016. PMID: 28168213 Free PMC article.
Prion-specific and surrogate CSF biomarkers in Creutzfeldt-Jakob disease: diagnostic accuracy in relation to molecular subtypes and analysis of neuropathological correlates of p-tau and Aβ42 levels.
Lattanzio F, Abu-Rumeileh S, Franceschini A, Kai H, Amore G, Poggiolini I, Rossi M, Baiardi S, McGuire L, Ladogana A, Pocchiari M, Green A, Capellari S, Parchi P. Lattanzio F, et al. Among authors: ladogana a. Acta Neuropathol. 2017 Apr;133(4):559-578. doi: 10.1007/s00401-017-1683-0. Epub 2017 Feb 15. Acta Neuropathol. 2017. PMID: 28205010 Free PMC article.
87 results