Ladbury JE - Search Results

1

Adding calorimetric data to decision making in lead discovery: a hot tip.

Ladbury JE, Klebe G, Freire E. Ladbury JE, et al. Nat Rev Drug Discov. 2010 Jan;9(1):23-7. doi: 10.1038/nrd3054. Epub 2009 Dec 4. Nat Rev Drug Discov. 2010. PMID: 19960014 Review.

2

Calorimetry as a tool for understanding biomolecular interactions and an aid to drug design.

Ladbury JE. Ladbury JE. Biochem Soc Trans. 2010 Aug;38(4):888-93. doi: 10.1042/BST0380888. Biochem Soc Trans. 2010. PMID: 20658972 Review.

3

The toolbox is open, but who should pay for the job?

Ladbury JE, Hall A, Skidmore J. Ladbury JE, et al. Nat Rev Drug Discov. 2014 Jul;13(7):479-80. doi: 10.1038/nrd4367. Nat Rev Drug Discov. 2014. PMID: 24981345 No abstract available.

4

Energetics of Src homology domain interactions in receptor tyrosine kinase-mediated signaling.

Ladbury JE, Arold ST. Ladbury JE, et al. Methods Enzymol. 2011;488:147-83. doi: 10.1016/B978-0-12-381268-1.00007-0. Methods Enzymol. 2011. PMID: 21195228

5

Probing cocaine-antibody interactions in buffer and human serum.

Ramakrishnan M, Alves De Melo F, Kinsey BM, Ladbury JE, Kosten TR, Orson FM. Ramakrishnan M, et al. Among authors: ladbury je. PLoS One. 2012;7(7):e40518. doi: 10.1371/journal.pone.0040518. Epub 2012 Jul 10. PLoS One. 2012. PMID: 22859949 Free PMC article.

6

Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression.

Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, Stagg LJ, Ladbury JE, Cai Z, Xu D, Logothetis CJ, Hung MC, Zhang S, Lin HK. Chan CH, et al. Among authors: ladbury je. Cell. 2013 Aug 1;154(3):556-68. doi: 10.1016/j.cell.2013.06.048. Cell. 2013. PMID: 23911321 Free PMC article.

7

Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli.

Suen KM, Lin CC, George R, Melo FA, Biggs ER, Ahmed Z, Drake MN, Arur S, Arold ST, Ladbury JE. Suen KM, et al. Among authors: ladbury je. Nat Struct Mol Biol. 2013 May;20(5):620-7. doi: 10.1038/nsmb.2557. Epub 2013 Apr 14. Nat Struct Mol Biol. 2013. PMID: 23584453 Free PMC article.

8

Grb2 monomer-dimer equilibrium determines normal versus oncogenic function.

Ahmed Z, Timsah Z, Suen KM, Cook NP, Lee GR 4th, Lin CC, Gagea M, Marti AA, Ladbury JE. Ahmed Z, et al. Among authors: ladbury je. Nat Commun. 2015 Jun 24;6:7354. doi: 10.1038/ncomms8354. Nat Commun. 2015. PMID: 26103942 Free PMC article.

9

Biophysical characterization of VEGF-aHt DNA aptamer interactions.

Kanakaraj I, Chen WH, Poongavanam M, Dhamane S, Stagg LJ, Ladbury JE, Kourentzi K, Strych U, Willson RC. Kanakaraj I, et al. Among authors: ladbury je. Int J Biol Macromol. 2013 Jun;57:69-75. doi: 10.1016/j.ijbiomac.2013.02.016. Epub 2013 Mar 5. Int J Biol Macromol. 2013. PMID: 23470436

10

Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.

Poncet-Montange G, Zhan Y, Bardenhagen JP, Petrocchi A, Leo E, Shi X, Lee GR 4th, Leonard PG, Geck Do MK, Cardozo MG, Andersen JN, Palmer WS, Jones P, Ladbury JE. Poncet-Montange G, et al. Among authors: ladbury je. Biochem J. 2015 Mar 1;466(2):337-46. doi: 10.1042/BJ20140933. Biochem J. 2015. PMID: 25486442 Free PMC article.

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