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Epitopes and Mechanism of Action of the Clostridium difficile Toxin A-Neutralizing Antibody Actoxumab.
Hernandez LD, Kroh HK, Hsieh E, Yang X, Beaumont M, Sheth PR, DiNunzio E, Rutherford SA, Ohi MD, Ermakov G, Xiao L, Secore S, Karczewski J, Racine F, Mayhood T, Fischer P, Sher X, Gupta P, Lacy DB, Therien AG. Hernandez LD, et al. Among authors: lacy db. J Mol Biol. 2017 Apr 7;429(7):1030-1044. doi: 10.1016/j.jmb.2017.02.010. Epub 2017 Feb 21. J Mol Biol. 2017. PMID: 28232034 Free PMC article.
Reconstitution of Helicobacter pylori VacA toxin from purified components.
González-Rivera C, Gangwer KA, McClain MS, Eli IM, Chambers MG, Ohi MD, Lacy DB, Cover TL. González-Rivera C, et al. Among authors: lacy db. Biochemistry. 2010 Jul 13;49(27):5743-52. doi: 10.1021/bi100618g. Biochemistry. 2010. PMID: 20527875 Free PMC article.
Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin.
Chambers MG, Pyburn TM, González-Rivera C, Collier SE, Eli I, Yip CK, Takizawa Y, Lacy DB, Cover TL, Ohi MD. Chambers MG, et al. Among authors: lacy db. J Mol Biol. 2013 Feb 8;425(3):524-35. doi: 10.1016/j.jmb.2012.11.020. Epub 2012 Nov 20. J Mol Biol. 2013. PMID: 23178866 Free PMC article.
Molecular assembly of botulinum neurotoxin progenitor complexes.
Benefield DA, Dessain SK, Shine N, Ohi MD, Lacy DB. Benefield DA, et al. Among authors: lacy db. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5630-5. doi: 10.1073/pnas.1222139110. Epub 2013 Mar 18. Proc Natl Acad Sci U S A. 2013. PMID: 23509303 Free PMC article.
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.
Quesada-Gómez C, López-Ureña D, Chumbler N, Kroh HK, Castro-Peña C, Rodríguez C, Orozco-Aguilar J, González-Camacho S, Rucavado A, Guzmán-Verri C, Lawley TD, Lacy DB, Chaves-Olarte E. Quesada-Gómez C, et al. Among authors: lacy db. Infect Immun. 2016 Jan 11;84(3):856-65. doi: 10.1128/IAI.01291-15. Infect Immun. 2016. PMID: 26755157 Free PMC article.
202 results