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The catalytic domains of Clostridium sordellii lethal toxin and related large clostridial glucosylating toxins specifically recognize the negatively charged phospholipids phosphatidylserine and phosphatidic acid.
Varela Chavez C, Hoos S, Haustant GM, Chenal A, England P, Blondel A, Pauillac S, Lacy DB, Popoff MR. Varela Chavez C, et al. Among authors: lacy db. Cell Microbiol. 2015 Oct;17(10):1477-93. doi: 10.1111/cmi.12449. Epub 2015 May 13. Cell Microbiol. 2015. PMID: 25882477
Crystal structure of Clostridium difficile toxin A.
Chumbler NM, Rutherford SA, Zhang Z, Farrow MA, Lisher JP, Farquhar E, Giedroc DP, Spiller BW, Melnyk RA, Lacy DB. Chumbler NM, et al. Among authors: lacy db. Nat Microbiol. 2016 Jan 11;1:15002. doi: 10.1038/nmicrobiol.2015.2. Nat Microbiol. 2016. PMID: 27571750 Free PMC article.
The role of toxins in Clostridium difficile infection.
Chandrasekaran R, Lacy DB. Chandrasekaran R, et al. Among authors: lacy db. FEMS Microbiol Rev. 2017 Nov 1;41(6):723-750. doi: 10.1093/femsre/fux048. FEMS Microbiol Rev. 2017. PMID: 29048477 Free PMC article. Review.
Structure and function of anthrax toxin.
Lacy DB, Collier RJ. Lacy DB, et al. Curr Top Microbiol Immunol. 2002;271:61-85. doi: 10.1007/978-3-662-05767-4_4. Curr Top Microbiol Immunol. 2002. PMID: 12224524 Review.
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