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Aged Nrf2-Null Mice Develop All Major Types of Age-Related Cataracts.
Rowan S, Jiang S, Francisco SG, Pomatto LCD, Ma Z, Jiao X, Campos MM, Aryal S, Patel SD, Mahaling B, Riazuddin SA, Duh EJ, Lachke SA, Hejtmancik JF, de Cabo R, FitzGerald PG, Taylor A. Rowan S, et al. Among authors: lachke sa. Invest Ophthalmol Vis Sci. 2021 Dec 1;62(15):10. doi: 10.1167/iovs.62.15.10. Invest Ophthalmol Vis Sci. 2021. PMID: 34882206 Free PMC article.
iSyTE: integrated Systems Tool for Eye gene discovery.
Lachke SA, Ho JW, Kryukov GV, O'Connell DJ, Aboukhalil A, Bulyk ML, Park PJ, Maas RL. Lachke SA, et al. Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1617-27. doi: 10.1167/iovs.11-8839. Print 2012 Mar. Invest Ophthalmol Vis Sci. 2012. PMID: 22323457 Free PMC article.
Pax6- and Six3-mediated induction of lens cell fate in mouse and human ES cells.
Anchan RM, Lachke SA, Gerami-Naini B, Lindsey J, Ng N, Naber C, Nickerson M, Cavallesco R, Rowan S, Eaton JL, Xi Q, Maas RL. Anchan RM, et al. Among authors: lachke sa. PLoS One. 2014 Dec 17;9(12):e115106. doi: 10.1371/journal.pone.0115106. eCollection 2014. PLoS One. 2014. PMID: 25517354 Free PMC article.
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology.
Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. Barnum CE, et al. Among authors: lachke sa. Hum Mol Genet. 2020 Jul 29;29(12):2076-2097. doi: 10.1093/hmg/ddaa096. Hum Mol Genet. 2020. PMID: 32420594 Free PMC article.
The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development.
Aryal S, Viet J, Weatherbee BAT, Siddam AD, Hernandez FG, Gautier-Courteille C, Paillard L, Lachke SA. Aryal S, et al. Among authors: lachke sa. Hum Genet. 2020 Dec;139(12):1541-1554. doi: 10.1007/s00439-020-02195-7. Epub 2020 Jun 27. Hum Genet. 2020. PMID: 32594240 Free PMC article.
79 results