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An early dysregulation of FAK and MEK/ERK signaling pathways precedes the β-amyloid deposition in the olfactory bulb of APP/PS1 mouse model of Alzheimer's disease.
Lachén-Montes M, González-Morales A, de Morentin XM, Pérez-Valderrama E, Ausín K, Zelaya MV, Serna A, Aso E, Ferrer I, Fernández-Irigoyen J, Santamaría E. Lachén-Montes M, et al. J Proteomics. 2016 Oct 4;148:149-58. doi: 10.1016/j.jprot.2016.07.032. Epub 2016 Aug 3. J Proteomics. 2016. PMID: 27498392
The olfactory bulb proteotype differs across frontotemporal dementia spectrum.
Lachén-Montes M, González-Morales A, Schvartz D, Zelaya MV, Ausin K, Fernández-Irigoyen J, Sánchez JC, Santamaría E. Lachén-Montes M, et al. J Proteomics. 2019 Jun 15;201:37-47. doi: 10.1016/j.jprot.2019.04.011. Epub 2019 Apr 15. J Proteomics. 2019. PMID: 30999060 Clinical Trial.
Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer's Disease.
Lachen-Montes M, González-Morales A, Palomino M, Ausin K, Gómez-Ochoa M, Zelaya MV, Ferrer I, Pérez-Mediavilla A, Fernández-Irigoyen J, Santamaría E. Lachen-Montes M, et al. Front Aging Neurosci. 2019 Jun 11;11:141. doi: 10.3389/fnagi.2019.00141. eCollection 2019. Front Aging Neurosci. 2019. PMID: 31244650 Free PMC article.
34 results