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NuA4 and H2A.Z control environmental responses and autotrophic growth in Arabidopsis.
Bieluszewski T, Sura W, Dziegielewski W, Bieluszewska A, Lachance C, Kabza M, Szymanska-Lejman M, Abram M, Wlodzimierz P, De Winne N, De Jaeger G, Sadowski J, Côté J, Ziolkowski PA. Bieluszewski T, et al. Among authors: lachance c. Nat Commun. 2022 Jan 12;13(1):277. doi: 10.1038/s41467-021-27882-5. Nat Commun. 2022. PMID: 35022409 Free PMC article.
Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation.
Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, Thomas T, Garcia BA, Liu WR, Strahl BD, Kono H, Li W, Shi X, Côté J, Kutateladze TG. Klein BJ, et al. Among authors: lachance c. Nat Commun. 2019 Oct 17;10(1):4724. doi: 10.1038/s41467-019-12551-5. Nat Commun. 2019. PMID: 31624313 Free PMC article.
MRG Proteins Are Shared by Multiple Protein Complexes With Distinct Functions.
Devoucoux M, Roques C, Lachance C, Lashgari A, Joly-Beauparlant C, Jacquet K, Alerasool N, Prudente A, Taipale M, Droit A, Lambert JP, Hussein SMI, Côté J. Devoucoux M, et al. Among authors: lachance c. Mol Cell Proteomics. 2022 Jul;21(7):100253. doi: 10.1016/j.mcpro.2022.100253. Epub 2022 May 28. Mol Cell Proteomics. 2022. PMID: 35636729 Free PMC article.
Recurrent chromosomal translocations in sarcomas create a megacomplex that mislocalizes NuA4/TIP60 to Polycomb target loci.
Sudarshan D, Avvakumov N, Lalonde ME, Alerasool N, Joly-Beauparlant C, Jacquet K, Mameri A, Lambert JP, Rousseau J, Lachance C, Paquet E, Herrmann L, Thonta Setty S, Loehr J, Bernardini MQ, Rouzbahman M, Gingras AC, Coulombe B, Droit A, Taipale M, Doyon Y, Côté J. Sudarshan D, et al. Among authors: lachance c. Genes Dev. 2022 Jun 1;36(11-12):664-683. doi: 10.1101/gad.348982.121. Epub 2022 Jun 16. Genes Dev. 2022. PMID: 35710139 Free PMC article.
Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Vann KR, Acharya A, Jang SM, Lachance C, Zandian M, Holt TA, Smith AL, Pandey K, Durden DL, El-Gamal D, Côté J, Byrareddy SN, Kutateladze TG. Vann KR, et al. Among authors: lachance c. Structure. 2022 Sep 1;30(9):1224-1232.e5. doi: 10.1016/j.str.2022.05.020. Epub 2022 Jun 17. Structure. 2022. PMID: 35716662 Free PMC article.
MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Becht DC, Klein BJ, Kanai A, Jang SM, Cox KL, Zhou BR, Phanor SK, Zhang Y, Chen RW, Ebmeier CC, Lachance C, Galloy M, Fradet-Turcotte A, Bulyk ML, Bai Y, Poirier MG, Côté J, Yokoyama A, Kutateladze TG. Becht DC, et al. Among authors: lachance c. Nat Commun. 2023 Feb 8;14(1):697. doi: 10.1038/s41467-023-36368-5. Nat Commun. 2023. PMID: 36754959 Free PMC article.
Guiding the HBO1 complex function through the JADE subunit.
Gaurav N, Kanai A, Lachance C, Cox KL, Liu J, Grzybowski AT, Saksouk N, Klein BJ, Komata Y, Asada S, Ruthenburg AJ, Poirier MG, Côté J, Yokoyama A, Kutateladze TG. Gaurav N, et al. Among authors: lachance c. Nat Struct Mol Biol. 2024 Mar 6. doi: 10.1038/s41594-024-01245-2. Online ahead of print. Nat Struct Mol Biol. 2024. PMID: 38448574
164 results