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Class-B GPCR activation: is ligand helix-capping the key?
Neumann JM, Couvineau A, Murail S, Lacapère JJ, Jamin N, Laburthe M. Neumann JM, et al. Among authors: laburthe m. Trends Biochem Sci. 2008 Jul;33(7):314-9. doi: 10.1016/j.tibs.2008.05.001. Epub 2008 Jun 12. Trends Biochem Sci. 2008. PMID: 18555686
Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.
Tan YV, Couvineau A, Laburthe M. Tan YV, et al. Among authors: laburthe m. J Biol Chem. 2004 Sep 10;279(37):38889-94. doi: 10.1074/jbc.M404460200. Epub 2004 Jul 6. J Biol Chem. 2004. PMID: 15247290 Free article.
We previously provided evidence for a physical contact between the side chain at position 22 of VIP and the N-terminal ectodomain of the hVPAC1 receptor (Tan, Y. V., Couvineau, A., Van Rampelbergh, J., and Laburthe, M. (2003) J. Biol. Chem. 278, 36531-36536). We exp …
We previously provided evidence for a physical contact between the side chain at position 22 of VIP and the N-terminal ectodomain of the hVP …
The vasoactive intestinal peptide (VIP) alpha-Helix up to C terminus interacts with the N-terminal ectodomain of the human VIP/Pituitary adenylate cyclase-activating peptide 1 receptor: photoaffinity, molecular modeling, and dynamics.
Ceraudo E, Murail S, Tan YV, Lacapère JJ, Neumann JM, Couvineau A, Laburthe M. Ceraudo E, et al. Among authors: laburthe m. Mol Endocrinol. 2008 Jan;22(1):147-55. doi: 10.1210/me.2007-0361. Epub 2007 Sep 20. Mol Endocrinol. 2008. PMID: 17885205 Free PMC article.
Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.
Couvineau A, Lacapere JJ, Tan YV, Rouyer-Fessard C, Nicole P, Laburthe M. Couvineau A, et al. Among authors: laburthe m. J Biol Chem. 2003 Jul 4;278(27):24759-66. doi: 10.1074/jbc.M301916200. Epub 2003 Apr 10. J Biol Chem. 2003. PMID: 12690118 Free article.
The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau, A. and Marie, J. C. (2002) Recept. Channels 8, 137-153), but nothing is known regarding the cytoplasmic domains responsible for AC activat …
The role of the N-terminal extracellular domain of hVPAC1 receptor for VIP binding is now established (Laburthe, M., Couvineau …
207 results