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Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
Beekhof R, Bertotti A, Böttger F, Vurchio V, Cottino F, Zanella ER, Migliardi G, Viviani M, Grassi E, Lupo B, Henneman AA, Knol JC, Pham TV, de Goeij-de Haas R, Piersma SR, Labots M, Verheul HMW, Trusolino L, Jimenez CR. Beekhof R, et al. Among authors: labots m. Sci Transl Med. 2023 Aug 16;15(709):eabm3687. doi: 10.1126/scitranslmed.abm3687. Epub 2023 Aug 16. Sci Transl Med. 2023. PMID: 37585503 Free article.
Effect of food on the pharmacokinetics of the WEE1 inhibitor adavosertib (AZD1775) in patients with advanced solid tumors.
Någård M, Ah-See ML, So K, Vermunt M, Thistlethwaite F, Labots M, Roxburgh P, Ravaud A, Campone M, Valkenburg-van Iersel L, Ottesen L, Li Y, Mugundu G. Någård M, et al. Among authors: labots m. Cancer Chemother Pharmacol. 2020 Jul;86(1):97-108. doi: 10.1007/s00280-020-04101-4. Epub 2020 Jun 16. Cancer Chemother Pharmacol. 2020. PMID: 32556602 Free PMC article. Clinical Trial.
[Endocrine side effects of checkpoint inhibitors].
Chen WJY, Krul-Poel YHM, Roth C, Labots M, van den Eertwegh AJM, Dreijerink KMA. Chen WJY, et al. Among authors: labots m. Ned Tijdschr Geneeskd. 2019 Oct 31;163:D3957. Ned Tijdschr Geneeskd. 2019. PMID: 31714042 Dutch.
Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.
Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Gotink KJ, et al. Among authors: labots m. Clin Cancer Res. 2011 Dec 1;17(23):7337-46. doi: 10.1158/1078-0432.CCR-11-1667. Epub 2011 Oct 6. Clin Cancer Res. 2011. PMID: 21980135 Free PMC article.
Genomic landscape of metastatic colorectal cancer.
Haan JC, Labots M, Rausch C, Koopman M, Tol J, Mekenkamp LJ, van de Wiel MA, Israeli D, van Essen HF, van Grieken NC, Voorham QJ, Bosch LJ, Qu X, Kabbarah O, Verheul HM, Nagtegaal ID, Punt CJ, Ylstra B, Meijer GA. Haan JC, et al. Among authors: labots m. Nat Commun. 2014 Nov 14;5:5457. doi: 10.1038/ncomms6457. Nat Commun. 2014. PMID: 25394515 Free PMC article. Clinical Trial.
57 results