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CCG•CGG interruptions in high-penetrance SCA8 families increase RAN translation and protein toxicity.
Perez BA, Shorrock HK, Banez-Coronel M, Zu T, Romano LE, Laboissonniere LA, Reid T, Ikeda Y, Reddy K, Gomez CM, Bird T, Ashizawa T, Schut LJ, Brusco A, Berglund JA, Hasholt LF, Nielsen JE, Subramony SH, Ranum LP. Perez BA, et al. Among authors: laboissonniere la. EMBO Mol Med. 2021 Nov 8;13(11):e14095. doi: 10.15252/emmm.202114095. Epub 2021 Oct 11. EMBO Mol Med. 2021. PMID: 34632710 Free PMC article.
Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Nguyen L, Montrasio F, Pattamatta A, Tusi SK, Bardhi O, Meyer KD, Hayes L, Nakamura K, Banez-Coronel M, Coyne A, Guo S, Laboissonniere LA, Gu Y, Narayanan S, Smith B, Nitsch RM, Kankel MW, Rushe M, Rothstein J, Zu T, Grimm J, Ranum LPW. Nguyen L, et al. Among authors: laboissonniere la. Neuron. 2020 Feb 19;105(4):645-662.e11. doi: 10.1016/j.neuron.2019.11.007. Epub 2019 Dec 9. Neuron. 2020. PMID: 31831332 Free PMC article.
Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs.
Nguyen L, Laboissonniere LA, Guo S, Pilotto F, Scheidegger O, Oestmann A, Hammond JW, Li H, Hyysalo A, Peltola R, Pattamatta A, Zu T, Voutilainen MH, Gelbard HA, Saxena S, Ranum LPW. Nguyen L, et al. Among authors: laboissonniere la. Neuron. 2020 Nov 25;108(4):784-796.e3. doi: 10.1016/j.neuron.2020.09.009. Epub 2020 Oct 5. Neuron. 2020. PMID: 33022226 Free PMC article.
ALS-associated genes display CNS expression in the developing zebrafish.
Laboissonniere LA, Smith CL, Mesenbrink J, Chowdhury R, Burney A, Lang M, Sierra M, Stark A, Maldonado-Casalduc G, Muller M, Trimarchi JM. Laboissonniere LA, et al. Gene Expr Patterns. 2018 Dec;30:14-31. doi: 10.1016/j.gep.2018.08.003. Epub 2018 Aug 27. Gene Expr Patterns. 2018. PMID: 30165106
Expression Profiling of Developing Zebrafish Retinal Cells.
Mullally M, Albrecht C, Horton M, Laboissonniere LA, Goetz JJ, Chowdhury R, Manning A, Wester AK, Bose Q, Trimarchi JM. Mullally M, et al. Among authors: laboissonniere la. Zebrafish. 2016 Aug;13(4):272-80. doi: 10.1089/zeb.2015.1184. Epub 2016 Mar 16. Zebrafish. 2016. PMID: 26982811
15 results