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Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework.
Chauhan V, Wilkins RC, Beaton D, Sachana M, Delrue N, Yauk C, O'Brien J, Marchetti F, Halappanavar S, Boyd M, Villeneuve D, Barton-Maclaren TS, Meek B, Anghel C, Heghes C, Barber C, Perkins E, Leblanc J, Burtt J, Laakso H, Laurier D, Lazo T, Whelan M, Thomas R, Cool D. Chauhan V, et al. Among authors: laakso h. Int J Radiat Biol. 2021;97(4):431-441. doi: 10.1080/09553002.2021.1884314. Epub 2021 Mar 1. Int J Radiat Biol. 2021. PMID: 33539251 Free PMC article.
Subjective vs informant-reported cognitive complaints have differential clinical significance in covert cerebral small vessel disease.
Arola A, Laakso HM, Heinonen H, Pitkänen J, Ahlström M, Lempiäinen J, Paajanen T, Virkkala J, Koikkalainen J, Lötjönen J, Korvenoja A, Melkas S, Jokinen H. Arola A, et al. Among authors: laakso hm. Cereb Circ Cogn Behav. 2023 Sep 9;5:100182. doi: 10.1016/j.cccb.2023.100182. eCollection 2023. Cereb Circ Cogn Behav. 2023. PMID: 37745893 Free PMC article.
Neurofilament light level correlates with brain atrophy, and cognitive and motor performance.
Kartau M, Melkas S, Kartau J, Arola A, Laakso H, Pitkänen J, Lempiäinen J, Koikkalainen J, Lötjönen J, Korvenoja A, Ahlström M, Herukka SK, Erkinjuntti T, Jokinen H. Kartau M, et al. Among authors: laakso h. Front Aging Neurosci. 2023 Jan 5;14:939155. doi: 10.3389/fnagi.2022.939155. eCollection 2022. Front Aging Neurosci. 2023. PMID: 36688160 Free PMC article.
AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice.
Kujala A, Valkonen E, Sallinen H, Tuppurainen L, Laakso H, Ylä-Herttuala E, Liimatainen T, Kujala J, Jokelainen O, Sironen R, Anttila M, Ylä-Herttuala S. Kujala A, et al. Among authors: laakso h. Front Med (Lausanne). 2022 Dec 8;9:1018208. doi: 10.3389/fmed.2022.1018208. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36569136 Free PMC article.
Event-recurring multiband SWIFT functional MRI with 200-ms temporal resolution during deep brain stimulation and isoflurane-induced burst suppression in rat.
Paasonen E, Paasonen J, Lehto LJ, Pirttimäki T, Laakso H, Wu L, Ma J, Idiyatullin D, Tanila H, Mangia S, Michaeli S, Gröhn O. Paasonen E, et al. Among authors: laakso h. Magn Reson Med. 2022 Jun;87(6):2872-2884. doi: 10.1002/mrm.29154. Epub 2022 Jan 5. Magn Reson Med. 2022. PMID: 34985145 Free PMC article.
Infantile status epilepticus disrupts myelin development.
Bencurova P, Laakso H, Salo RA, Paasonen E, Manninen E, Paasonen J, Michaeli S, Mangia S, Bares M, Brazdil M, Kubova H, Gröhn O. Bencurova P, et al. Among authors: laakso h. Neurobiol Dis. 2022 Jan;162:105566. doi: 10.1016/j.nbd.2021.105566. Epub 2021 Nov 24. Neurobiol Dis. 2022. PMID: 34838665 Free PMC article.
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