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Page 1
Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.
Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, Bandell M, Schmedt C, Wengelnik K, Su AI, Honore E, Winzeler EA, Andersen KG, Patapoutian A. Ma S, et al. Among authors: lamonte g. Cell. 2018 Apr 5;173(2):443-455.e12. doi: 10.1016/j.cell.2018.02.047. Epub 2018 Mar 22. Cell. 2018. PMID: 29576450 Free PMC article.
Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor.
Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Murray R, Prescott M, McNamara CW, Slayman CW, Amaro RE, Suzuki Y, Winzeler EA. Goldgof GM, et al. Sci Rep. 2016 Jun 13;6:27806. doi: 10.1038/srep27806. Sci Rep. 2016. PMID: 27291296 Free PMC article.
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.
LaMonte GM, Almaliti J, Bibo-Verdugo B, Keller L, Zou BY, Yang J, Antonova-Koch Y, Orjuela-Sanchez P, Boyle CA, Vigil E, Wang L, Goldgof GM, Gerwick L, O'Donoghue AJ, Winzeler EA, Gerwick WH, Ottilie S. LaMonte GM, et al. J Med Chem. 2017 Aug 10;60(15):6721-6732. doi: 10.1021/acs.jmedchem.7b00671. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28696697 Free PMC article.
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.
LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA. LaMonte GM, et al. Nat Commun. 2020 Apr 14;11(1):1780. doi: 10.1038/s41467-020-15440-4. Nat Commun. 2020. PMID: 32286267 Free PMC article.
Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors.
Almaliti J, Fajtová P, Calla J, LaMonte GM, Feng M, Rocamora F, Ottilie S, Glukhov E, Boura E, Suhandynata RT, Momper JD, Gilson MK, Winzeler EA, Gerwick WH, O'Donoghue AJ. Almaliti J, et al. Among authors: lamonte gm. Chemistry. 2023 Apr 6;29(20):e202203958. doi: 10.1002/chem.202203958. Epub 2023 Mar 6. Chemistry. 2023. PMID: 36617500 Free PMC article.
UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.
Lim MY, LaMonte G, Lee MCS, Reimer C, Tan BH, Corey V, Tjahjadi BF, Chua A, Nachon M, Wintjens R, Gedeck P, Malleret B, Renia L, Bonamy GMC, Ho PC, Yeung BKS, Chow ED, Lim L, Fidock DA, Diagana TT, Winzeler EA, Bifani P. Lim MY, et al. Among authors: lamonte g. Nat Microbiol. 2016 Sep 19;1:16166. doi: 10.1038/nmicrobiol.2016.166. Nat Microbiol. 2016. PMID: 27642791 Free PMC article.
21 results