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Enantiomers of C(5)-chiral 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives: Analytical and semipreparative HPLC separation, chiroptical properties, absolute configuration, and inhibitory activity against monoamine oxidase.
Cirilli R, Ferretti R, Gallinella B, Turchetto L, Bolasco A, Secci D, Chimenti P, Pierini M, Fares V, Befani O, La Torre F. Cirilli R, et al. Among authors: la torre f. Chirality. 2004 Nov;16(9):625-36. doi: 10.1002/chir.20085. Chirality. 2004. PMID: 15382204
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)- pyrazole derivatives.
Chimenti F, Maccioni E, Secci D, Bolasco A, Chimenti P, Granese A, Befani O, Turini P, Alcaro S, Ortuso F, Cirilli R, La Torre F, Cardia MC, Distinto S. Chimenti F, et al. Among authors: la torre f. J Med Chem. 2005 Nov 17;48(23):7113-22. doi: 10.1021/jm040903t. J Med Chem. 2005. PMID: 16279769
Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors.
Chimenti F, Bolasco A, Manna F, Secci D, Chimenti P, Granese A, Befani O, Turini P, Cirilli R, La Torre F, Alcaro S, Ortuso F, Langer T. Chimenti F, et al. Among authors: la torre f. Curr Med Chem. 2006;13(12):1411-28. doi: 10.2174/092986706776872907. Curr Med Chem. 2006. PMID: 16719786 Review.
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.
Chimenti F, Maccioni E, Secci D, Bolasco A, Chimenti P, Granese A, Carradori S, Alcaro S, Ortuso F, Yáñez M, Orallo F, Cirilli R, Ferretti R, La Torre F. Chimenti F, et al. Among authors: la torre f. J Med Chem. 2008 Aug 28;51(16):4874-80. doi: 10.1021/jm800132g. Epub 2008 Jul 31. J Med Chem. 2008. PMID: 18666768
1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies.
La Regina G, D'Auria FD, Tafi A, Piscitelli F, Olla S, Caporuscio F, Nencioni L, Cirilli R, La Torre F, De Melo NR, Kelly SL, Lamb DC, Artico M, Botta M, Palamara AT, Silvestri R. La Regina G, et al. Among authors: la torre f. J Med Chem. 2008 Jul 10;51(13):3841-55. doi: 10.1021/jm800009r. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18529046
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.
Biava M, Porretta GC, Poce G, Supino S, Manetti F, Forli S, Botta M, Sautebin L, Rossi A, Pergola C, Ghelardini C, Norcini M, Makovec F, Giordani A, Anzellotti P, Cirilli R, Ferretti R, Gallinella B, La Torre F, Anzini M, Patrignani P. Biava M, et al. Among authors: la torre f. Bioorg Med Chem. 2008 Sep 1;16(17):8072-81. doi: 10.1016/j.bmc.2008.07.058. Epub 2008 Jul 24. Bioorg Med Chem. 2008. PMID: 18752957
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
Piscitelli F, Coluccia A, Brancale A, La Regina G, Sansone A, Giordano C, Balzarini J, Maga G, Zanoli S, Samuele A, Cirilli R, La Torre F, Lavecchia A, Novellino E, Silvestri R. Piscitelli F, et al. Among authors: la torre f, la regina g. J Med Chem. 2009 Apr 9;52(7):1922-34. doi: 10.1021/jm801470b. J Med Chem. 2009. PMID: 19281225
325 results