La Thangue N - Search Results

1

Selective inhibition of BET bromodomains.

Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Filippakopoulos P, et al. Among authors: la thangue n. Nature. 2010 Dec 23;468(7327):1067-73. doi: 10.1038/nature09504. Epub 2010 Sep 24. Nature. 2010. PMID: 20871596 Free PMC article.

2

DNA-damage-responsive acetylation of pRb regulates binding to E2F-1.

Markham D, Munro S, Soloway J, O'Connor DP, La Thangue NB. Markham D, et al. EMBO Rep. 2006 Feb;7(2):192-8. doi: 10.1038/sj.embor.7400591. EMBO Rep. 2006. PMID: 16374512 Free PMC article.

3

A functionally distinct member of the DP family of E2F subunits.

Milton A, Luoto K, Ingram L, Munro S, Logan N, Graham AL, Brummelkamp TR, Hijmans EM, Bernards R, La Thangue NB. Milton A, et al. Among authors: la thangue nb. Oncogene. 2006 May 25;25(22):3212-8. doi: 10.1038/sj.onc.1209343. Oncogene. 2006. PMID: 16418725

4

Arginine methylation regulates the p53 response.

Jansson M, Durant ST, Cho EC, Sheahan S, Edelmann M, Kessler B, La Thangue NB. Jansson M, et al. Nat Cell Biol. 2008 Dec;10(12):1431-9. doi: 10.1038/ncb1802. Epub 2008 Nov 16. Nat Cell Biol. 2008. PMID: 19011621

5

Lysine methylation regulates the pRb tumour suppressor protein.

Munro S, Khaire N, Inche A, Carr S, La Thangue NB. Munro S, et al. Among authors: la thangue nb. Oncogene. 2010 Apr 22;29(16):2357-67. doi: 10.1038/onc.2009.511. Epub 2010 Feb 8. Oncogene. 2010. PMID: 20140018

6

E2F-1 regulation by an unusual DNA damage-responsive DP partner subunit.

Ingram L, Munro S, Coutts AS, La Thangue NB. Ingram L, et al. Among authors: la thangue nb. Cell Death Differ. 2011 Jan;18(1):122-32. doi: 10.1038/cdd.2010.70. Epub 2010 Jun 18. Cell Death Differ. 2011. PMID: 20559320 Free PMC article.

7

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.

Carr SM, Munro S, Kessler B, Oppermann U, La Thangue NB. Carr SM, et al. EMBO J. 2011 Jan 19;30(2):317-27. doi: 10.1038/emboj.2010.311. Epub 2010 Nov 30. EMBO J. 2011. PMID: 21119616 Free PMC article.

8

Diversity within the pRb pathway: is there a code of conduct?

Munro S, Carr SM, La Thangue NB. Munro S, et al. Among authors: la thangue nb. Oncogene. 2012 Oct 4;31(40):4343-52. doi: 10.1038/onc.2011.603. Epub 2012 Jan 16. Oncogene. 2012. PMID: 22249267 Review.

9

The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.

Adams CJ, Pike AC, Maniam S, Sharpe TD, Coutts AS, Knapp S, La Thangue NB, Bullock AN. Adams CJ, et al. Among authors: la thangue nb. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3778-83. doi: 10.1073/pnas.1113731109. Epub 2012 Feb 23. Proc Natl Acad Sci U S A. 2012. PMID: 22362889 Free PMC article.

10

Lysine methylation and the regulation of p53.

Carr SM, Munro S, La Thangue NB. Carr SM, et al. Essays Biochem. 2012;52:79-92. doi: 10.1042/bse0520079. Essays Biochem. 2012. PMID: 22708565 Review.

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