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Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.
Rullo M, La Spada G, Miniero DV, Gottinger A, Catto M, Delre P, Mastromarino M, Latronico T, Marchese S, Mangiatordi GF, Binda C, Linusson A, Liuzzi GM, Pisani L. Rullo M, et al. Among authors: la spada g. Eur J Med Chem. 2023 Jul 5;255:115352. doi: 10.1016/j.ejmech.2023.115352. Epub 2023 Apr 8. Eur J Med Chem. 2023. PMID: 37178666
Functional diversity of nanohaloarchaea within xylan-degrading consortia.
Reva O, Messina E, La Cono V, Crisafi F, Smedile F, La Spada G, Marturano L, Selivanova EA, Rohde M, Krupovic M, Yakimov MM. Reva O, et al. Among authors: la spada g. Front Microbiol. 2023 May 31;14:1182464. doi: 10.3389/fmicb.2023.1182464. eCollection 2023. Front Microbiol. 2023. PMID: 37323909 Free PMC article.
Nanohaloarchaea as beneficiaries of xylan degradation by haloarchaea.
La Cono V, Messina E, Reva O, Smedile F, La Spada G, Crisafi F, Marturano L, Miguez N, Ferrer M, Selivanova EA, Golyshina OV, Golyshin PN, Rohde M, Krupovic M, Merkel AY, Sorokin DY, Hallsworth JE, Yakimov MM. La Cono V, et al. Among authors: la spada g. Microb Biotechnol. 2023 Sep;16(9):1803-1822. doi: 10.1111/1751-7915.14272. Epub 2023 Jun 14. Microb Biotechnol. 2023. PMID: 37317055 Free PMC article.
Symbiosis between nanohaloarchaeon and haloarchaeon is based on utilization of different polysaccharides.
La Cono V, Messina E, Rohde M, Arcadi E, Ciordia S, Crisafi F, Denaro R, Ferrer M, Giuliano L, Golyshin PN, Golyshina OV, Hallsworth JE, La Spada G, Mena MC, Merkel AY, Shevchenko MA, Smedile F, Sorokin DY, Toshchakov SV, Yakimov MM. La Cono V, et al. Among authors: la spada g. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20223-20234. doi: 10.1073/pnas.2007232117. Epub 2020 Aug 5. Proc Natl Acad Sci U S A. 2020. PMID: 32759215 Free PMC article.
55 results