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Copper and Copper Complexes in Tumor Therapy.
Wang Y, Tang T, Yuan Y, Li N, Wang X, Guan J. Wang Y, et al. ChemMedChem. 2024 Mar 5:e202400060. doi: 10.1002/cmdc.202400060. Online ahead of print. ChemMedChem. 2024. PMID: 38443744 Review.
The development of drugs that target copper homeostasis has emerged as a promising strategy for anticancer treatment, with a particular focus on copper chelators, copper ionophores, and novel copper complexes. Recent research has also investigated the potential of copper c …
The development of drugs that target copper homeostasis has emerged as a promising strategy for anticancer treatment, with a particular focu …
Cancer-associated fibroblasts promote the survival of irradiated nasopharyngeal carcinoma cells via the NF-κB pathway.
Huang W, Zhang L, Yang M, Wu X, Wang X, Huang W, Yuan L, Pan H, Wang Y, Wang Z, Wu Y, Huang J, Liang H, Li S, Liao L, Liu L, Guan J. Huang W, et al. J Exp Clin Cancer Res. 2021 Mar 1;40(1):87. doi: 10.1186/s13046-021-01878-x. J Exp Clin Cancer Res. 2021. PMID: 33648530 Free PMC article.
RESULTS: We found that radiation-resistant NPC tissues were constantly infiltrated with a greater number of cancer-associated fibroblasts (CAFs) compared to radiosensitive NPC tissues. Further research revealed that CAFs induced the formation of radioresistance and promote …
RESULTS: We found that radiation-resistant NPC tissues were constantly infiltrated with a greater number of cancer-associated fibroblasts (C …