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Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.
Bosch-Queralt M, Cantuti-Castelvetri L, Damkou A, Schifferer M, Schlepckow K, Alexopoulos I, Lütjohann D, Klose C, Vaculčiaková L, Masuda T, Prinz M, Monroe KM, Di Paolo G, Lewcock JW, Haass C, Simons M. Bosch-Queralt M, et al. Among authors: lutjohann d. Nat Metab. 2021 Feb;3(2):211-227. doi: 10.1038/s42255-021-00341-7. Epub 2021 Feb 18. Nat Metab. 2021. PMID: 33619376 Free PMC article.
Defective cholesterol clearance limits remyelination in the aged central nervous system.
Cantuti-Castelvetri L, Fitzner D, Bosch-Queralt M, Weil MT, Su M, Sen P, Ruhwedel T, Mitkovski M, Trendelenburg G, Lütjohann D, Möbius W, Simons M. Cantuti-Castelvetri L, et al. Among authors: lutjohann d. Science. 2018 Feb 9;359(6376):684-688. doi: 10.1126/science.aan4183. Epub 2018 Jan 4. Science. 2018. PMID: 29301957
Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.
Bosch-Queralt M, Cantuti-Castelvetri L, Damkou A, Schifferer M, Schlepckow K, Alexopoulos I, Lütjohann D, Klose C, Vaculčiaková L, Masuda T, Prinz M, Monroe KM, Di Paolo G, Lewcock JW, Haass C, Simons M. Bosch-Queralt M, et al. Among authors: lutjohann d. Nat Metab. 2023 Mar;5(3):531. doi: 10.1038/s42255-023-00750-w. Nat Metab. 2023. PMID: 36823473 No abstract available.
Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.
Vanmierlo T, Weingärtner O, van der Pol S, Husche C, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch H, Grimm M, Hartmann T, Laufs U, Böhm M, de Vries HE, Mulder M, Lütjohann D. Vanmierlo T, et al. Among authors: lutjohann d. J Lipid Res. 2012 Apr;53(4):726-35. doi: 10.1194/jlr.M017244. Epub 2012 Jan 25. J Lipid Res. 2012. PMID: 22279184 Free PMC article.
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. De Nardo D, et al. Among authors: lutjohann d. Nat Immunol. 2014 Feb;15(2):152-60. doi: 10.1038/ni.2784. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317040 Free PMC article.
Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis.
Schierwagen R, Maybüchen L, Zimmer S, Hittatiya K, Bäck C, Klein S, Uschner FE, Reul W, Boor P, Nickenig G, Strassburg CP, Trautwein C, Plat J, Lütjohann D, Sauerbruch T, Tacke F, Trebicka J. Schierwagen R, et al. Among authors: lutjohann d. Sci Rep. 2015 Aug 11;5:12931. doi: 10.1038/srep12931. Sci Rep. 2015. PMID: 26263022 Free PMC article.
Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.
Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Tamboli IY, et al. Among authors: lutjohann d. J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008. J Neurosci. 2008. PMID: 19005074 Free PMC article.
410 results