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Page 1
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
Auffenberg E, Hedrich UB, Barbieri R, Miely D, Groschup B, Wuttke TV, Vogel N, Lührs P, Zanardi I, Bertelli S, Spielmann N, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Pusch M, Dichgans M, Lerche H, Gavazzo P, Plesnila N, Freilinger T. Auffenberg E, et al. Among authors: luhrs p. J Clin Invest. 2021 Nov 1;131(21):e142202. doi: 10.1172/JCI142202. J Clin Invest. 2021. PMID: 34546973 Free PMC article.
Safety and Tolerability of Active Immunotherapy Targeting α-Synuclein with PD03A in Patients with Early Parkinson's Disease: A Randomized, Placebo-Controlled, Phase 1 Study.
Poewe W, Volc D, Seppi K, Medori R, Lührs P, Kutzelnigg A, Djamshidian A, Thun-Hohenstein C, Meissner WG, Rascol O, Schneeberger A, Staffler G; AFF011 investigators; AFF011 study investigators:; Poewe W, Seppi K, Djamshidian A, deMarzi R, Heim B, Mangesius S, Stolz R, Wachowicz K, Volc D, Thun-Hohenstein C, Riha C, Schneeberger A, Bürger V, Galabova G. Poewe W, et al. Among authors: luhrs p. J Parkinsons Dis. 2021;11(3):1079-1089. doi: 10.3233/JPD-212594. J Parkinsons Dis. 2021. PMID: 34092654 Free PMC article. Clinical Trial.
A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9.
Zeitlinger M, Bauer M, Reindl-Schwaighofer R, Stoekenbroek RM, Lambert G, Berger-Sieczkowski E, Lagler H, Oesterreicher Z, Wulkersdorfer B, Lührs P, Galabova G, Schwenke C, Mader RM, Medori R, Landlinger C, Kutzelnigg A, Staffler G. Zeitlinger M, et al. Among authors: luhrs p. Eur J Clin Pharmacol. 2021 Oct;77(10):1473-1484. doi: 10.1007/s00228-021-03149-2. Epub 2021 May 10. Eur J Clin Pharmacol. 2021. PMID: 33969434 Free PMC article. Clinical Trial.
A Phase 1 Randomized Trial of Specific Active α-Synuclein Immunotherapies PD01A and PD03A in Multiple System Atrophy.
Meissner WG, Traon AP, Foubert-Samier A, Galabova G, Galitzky M, Kutzelnigg A, Laurens B, Lührs P, Medori R, Péran P, Sabatini U, Vergnet S, Volc D, Poewe W, Schneeberger A, Staffler G, Rascol O; AFF009 Study Investigators. Meissner WG, et al. Among authors: luhrs p. Mov Disord. 2020 Nov;35(11):1957-1965. doi: 10.1002/mds.28218. Epub 2020 Sep 3. Mov Disord. 2020. PMID: 32882100 Free PMC article. Clinical Trial.
Safety and immunogenicity of the α-synuclein active immunotherapeutic PD01A in patients with Parkinson's disease: a randomised, single-blinded, phase 1 trial.
Volc D, Poewe W, Kutzelnigg A, Lührs P, Thun-Hohenstein C, Schneeberger A, Galabova G, Majbour N, Vaikath N, El-Agnaf O, Winter D, Mihailovska E, Mairhofer A, Schwenke C, Staffler G, Medori R. Volc D, et al. Among authors: luhrs p. Lancet Neurol. 2020 Jul;19(7):591-600. doi: 10.1016/S1474-4422(20)30136-8. Lancet Neurol. 2020. PMID: 32562684 Clinical Trial.
Peptide-based anti-PCSK9 vaccines - an approach for long-term LDLc management.
Galabova G, Brunner S, Winsauer G, Juno C, Wanko B, Mairhofer A, Lührs P, Schneeberger A, von Bonin A, Mattner F, Schmidt W, Staffler G. Galabova G, et al. Among authors: luhrs p. PLoS One. 2014 Dec 4;9(12):e114469. doi: 10.1371/journal.pone.0114469. eCollection 2014. PLoS One. 2014. PMID: 25474576 Free PMC article.
CpG motifs are efficient adjuvants for DNA cancer vaccines.
Schneeberger A, Wagner C, Zemann A, Lührs P, Kutil R, Goos M, Stingl G, Wagner SN. Schneeberger A, et al. Among authors: luhrs p. J Invest Dermatol. 2004 Aug;123(2):371-9. doi: 10.1111/j.0022-202X.2004.23208.x. J Invest Dermatol. 2004. PMID: 15245438 Free article.
13 results