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Chimeric antigen receptor T cells targeting the GM3(Neu5Gc) ganglioside.
Heinzelbecker J, Fauskanger M, Jonson I, Krengel U, Løset GÅ, Munthe L, Tveita A. Heinzelbecker J, et al. Among authors: loset ga. Front Immunol. 2024 Feb 2;15:1331345. doi: 10.3389/fimmu.2024.1331345. eCollection 2024. Front Immunol. 2024. PMID: 38370401 Free PMC article.
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.
Bjerregaard-Andersen K, Johannesen H, Abdel-Rahman N, Heggelund JE, Hoås HM, Abraha F, Bousquet PA, Høydahl LS, Burschowsky D, Rojas G, Oscarson S, Løset GÅ, Krengel U. Bjerregaard-Andersen K, et al. Among authors: loset ga. Sci Rep. 2018 Jul 18;8(1):10836. doi: 10.1038/s41598-018-28918-5. Sci Rep. 2018. PMID: 30022069 Free PMC article.
A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ. Frick R, et al. Among authors: loset ga. Sci Immunol. 2021 Aug 20;6(62):eabg4925. doi: 10.1126/sciimmunol.abg4925. Sci Immunol. 2021. PMID: 34417258 Free PMC article.
36 results