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Page 1
The roles of peripheral serotonin in metabolic homeostasis.
El-Merahbi R, Löffler M, Mayer A, Sumara G. El-Merahbi R, et al. FEBS Lett. 2015 Jul 8;589(15):1728-34. doi: 10.1016/j.febslet.2015.05.054. Epub 2015 Jun 9. FEBS Lett. 2015. PMID: 26070423 Free article. Review.
Protein Kinase D2 drives chylomicron-mediated lipid transport in the intestine and promotes obesity.
Trujillo-Viera J, El-Merahbi R, Schmidt V, Karwen T, Loza-Valdes A, Strohmeyer A, Reuter S, Noh M, Wit M, Hawro I, Mocek S, Fey C, Mayer AE, Löffler MC, Wilhelmi I, Metzger M, Ishikawa E, Yamasaki S, Rau M, Geier A, Hankir M, Seyfried F, Klingenspor M, Sumara G. Trujillo-Viera J, et al. Among authors: loffler mc. EMBO Mol Med. 2021 May 7;13(5):e13548. doi: 10.15252/emmm.202013548. Epub 2021 May 5. EMBO Mol Med. 2021. PMID: 33949105 Free PMC article.
Targeting ERK3/MK5 complex for treatment of obesity and diabetes.
Loza-Valdes A, El-Merahbi R, Kassouf T, Demczuk A, Reuter S, Viera JT, Karwen T, Noh M, Löffler MC, Romero-Becerra R, Torres JL, Marcos M, Sabio G, Wojda U, Sumara G. Loza-Valdes A, et al. Among authors: loffler mc. Biochem Biophys Res Commun. 2022 Jul 5;612:119-125. doi: 10.1016/j.bbrc.2022.04.070. Epub 2022 Apr 27. Biochem Biophys Res Commun. 2022. PMID: 35523049 Free article.
Platelet-derived lipids promote insulin secretion of pancreatic β cells.
Karwen T, Kolczynska-Matysiak K, Gross C, Löffler MC, Friedrich M, Loza-Valdes A, Schmitz W, Wit M, Dziaczkowski F, Belykh A, Trujillo-Viera J, El-Merahbi R, Deppermann C, Nawaz S, Hastoy B, Demczuk A, Erk M, Wieckowski MR, Rorsman P, Heinze KG, Stegner D, Nieswandt B, Sumara G. Karwen T, et al. Among authors: loffler mc. EMBO Mol Med. 2023 Sep 11;15(9):e16858. doi: 10.15252/emmm.202216858. Epub 2023 Jul 25. EMBO Mol Med. 2023. PMID: 37490001 Free PMC article.
Identification of a regulatory pathway inhibiting adipogenesis via RSPO2.
Dong H, Sun W, Shen Y, Baláz M, Balázová L, Ding L, Löffler M, Hamilton B, Klöting N, Blüher M, Neubauer H, Klein H, Wolfrum C. Dong H, et al. Nat Metab. 2022 Jan;4(1):90-105. doi: 10.1038/s42255-021-00509-1. Epub 2022 Jan 13. Nat Metab. 2022. PMID: 35027768 Free PMC article.