Löffler M - Search Results

1

Synthesis of beta-hydroxy-propenamide derivatives and the inhibition of human dihydroorotate dehydrogenase.

Kim TH, Na HS, Löffler M. Kim TH, et al. Among authors: loffler m. Arch Pharm Res. 2003 Mar;26(3):197-201. doi: 10.1007/BF02976829. Arch Pharm Res. 2003. PMID: 12723931

2

Knecht W, Löffler M. Knecht W, et al. Among authors: loffler m. Biochem Pharmacol. 1998 Nov 1;56(9):1259-64. doi: 10.1016/s0006-2952(98)00145-2. Biochem Pharmacol. 1998. PMID: 9802339

3

Dihydroorotate dehydrogenase mRNA and protein expression analysis in normal and drug-resistant cells.

Löffler M, Klein A, Hayek-Ouassini M, Knecht W, Konrad L. Löffler M, et al. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1281-5. doi: 10.1081/NCN-200027547. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571246

4

Immunocytochemical detection of mitochondrial dihydroorotate dehydrogenase in human spermatozoa.

Dietz C, Hinsch E, Löffler M. Dietz C, et al. Among authors: loffler m. Int J Androl. 2000 Oct;23(5):294-9. doi: 10.1046/j.1365-2605.2000.00246.x. Int J Androl. 2000. PMID: 11012787

5

Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid.

Knecht W, Henseling J, Löffler M. Knecht W, et al. Among authors: loffler m. Chem Biol Interact. 2000 Jan 3;124(1):61-76. doi: 10.1016/s0009-2797(99)00144-1. Chem Biol Interact. 2000. PMID: 10658902

Another inhibitor, brequinar was previously reported to be a slow-binding inhibitor of the human dihydroorotate dehydrogenase [W. Knecht, M. Loffler, Species-related inhibition of human and rat dihyroorotate dehydrogenase by immunosuppressive isoxazol and cinchonini …

Another inhibitor, brequinar was previously reported to be a slow-binding inhibitor of the human dihydroorotate dehydrogenase [W. Knecht, …

6

Plant dihydroorotate dehydrogenase differs significantly in substrate specificity and inhibition from the animal enzymes.

Ullrich A, Knecht W, Piskur J, Löffler M. Ullrich A, et al. Among authors: loffler m. FEBS Lett. 2002 Oct 9;529(2-3):346-50. doi: 10.1016/s0014-5793(02)03425-7. FEBS Lett. 2002. PMID: 12372626 Free article.

7

Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.

Zameitat E, Gojković Z, Knecht W, Piskur J, Löffler M. Zameitat E, et al. Among authors: loffler m. FEBS J. 2006 Jul;273(14):3183-91. doi: 10.1111/j.1742-4658.2006.05327.x. Epub 2006 Jun 15. FEBS J. 2006. PMID: 16774642 Free article.

8

Redoxal as a new lead structure for dihydroorotate dehydrogenase inhibitors: a kinetic study of the inhibition mechanism.

Knecht W, Löffler M. Knecht W, et al. Among authors: loffler m. FEBS Lett. 2000 Feb 4;467(1):27-30. doi: 10.1016/s0014-5793(00)01117-0. FEBS Lett. 2000. PMID: 10664450 Free article.

9

Dihydroorotate dehydrogenase from Saccharomyces cerevisiae: spectroscopic investigations with the recombinant enzyme throw light on catalytic properties and metabolism of fumarate analogues.

Zameitat E, Pierik AJ, Zocher K, Löffler M. Zameitat E, et al. Among authors: loffler m. FEMS Yeast Res. 2007 Sep;7(6):897-904. doi: 10.1111/j.1567-1364.2007.00275.x. Epub 2007 Jul 6. FEMS Yeast Res. 2007. PMID: 17617217

10

Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domain.

Hansen M, Le Nours J, Johansson E, Antal T, Ullrich A, Löffler M, Larsen S. Hansen M, et al. Among authors: loffler m. Protein Sci. 2004 Apr;13(4):1031-42. doi: 10.1110/ps.03533004. Protein Sci. 2004. PMID: 15044733 Free PMC article.

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