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Discovery, synthesis and in combo studies of a tetrazole analogue of clofibric acid as a potent hypoglycemic agent.
Navarrete-Vázquez G, Alaniz-Palacios A, Hidalgo-Figueroa S, González-Acevedo C, Ávila-Villarreal G, Estrada-Soto S, Webster SP, Medina-Franco JL, López-Vallejo F, Guerrero-Álvarez J, Tlahuext H. Navarrete-Vázquez G, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3244-7. doi: 10.1016/j.bmcl.2013.03.122. Epub 2013 Apr 5. Bioorg Med Chem Lett. 2013. PMID: 23597793
Synthesis, in vitro and in silico screening of ethyl 2-(6-substituted benzo[d]thiazol-2-ylamino)-2-oxoacetates as protein-tyrosine phosphatase 1B inhibitors.
Navarrete-Vazquez G, Ramírez-Martínez M, Estrada-Soto S, Nava-Zuazo C, Paoli P, Camici G, Escalante-García J, Medina-Franco JL, López-Vallejo F, Ortiz-Andrade R. Navarrete-Vazquez G, et al. Eur J Med Chem. 2012 Jul;53:346-55. doi: 10.1016/j.ejmech.2012.04.025. Epub 2012 Apr 26. Eur J Med Chem. 2012. PMID: 22583779
Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl)amino]-1,3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities.
Navarrete-Vázquez G, Morales-Vilchis MG, Estrada-Soto S, Ramírez-Espinosa JJ, Hidalgo-Figueroa S, Nava-Zuazo C, Tlahuext H, Leon-Rivera I, Medina-Franco JL, López-Vallejo F, Webster SP, Binnie M, Ortiz-Andrade R, Moreno-Diaz H. Navarrete-Vázquez G, et al. Eur J Med Chem. 2014 Mar 3;74:179-86. doi: 10.1016/j.ejmech.2013.12.042. Epub 2014 Jan 8. Eur J Med Chem. 2014. PMID: 24462849
Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies.
Rios MY, López-Martínez S, López-Vallejo F, Medina-Franco JL, Villalobos-Molina R, Ibarra-Barajas M, Navarrete-Vazquez G, Hidalgo-Figueroa S, Hernández-Abreu O, Estrada-Soto S. Rios MY, et al. Fitoterapia. 2012 Sep;83(6):1023-9. doi: 10.1016/j.fitote.2012.05.014. Epub 2012 May 29. Fitoterapia. 2012. PMID: 22659049
35 results