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Page 1
Dysregulation of Components of the Inflammasome Machinery After Bariatric Surgery: Novel Targets for a Chronic Disease.
Herrero-Aguayo V, Sáez-Martínez P, López-Cánovas JL, Prados-Carmona JJ, Alcántara-Laguna MD, López FL, Molina-Puerta MJ, Calañas-Continente A, Membrives A, Castilla J, Ruiz-Ravelo J, Alonso-Echague R, Yubero-Serrano EM, Castaño JP, Gahete MD, Gálvez-Moreno MA, Luque RM, Herrera-Martínez AD. Herrero-Aguayo V, et al. Among authors: lopez canovas jl. J Clin Endocrinol Metab. 2021 Nov 19;106(12):e4917-e4934. doi: 10.1210/clinem/dgab586. J Clin Endocrinol Metab. 2021. PMID: 34363480
Influence of Obesity in the miRNome: miR-4454, a Key Regulator of Insulin Response Via Splicing Modulation in Prostate.
Herrero-Aguayo V, Jiménez-Vacas JM, Sáez-Martínez P, Gómez-Gómez E, López-Cánovas JL, Garrido-Sánchez L, Herrera-Martínez AD, García-Bermejo L, Macías-González M, López-Miranda J, Castaño JP, Gahete MD, Luque RM. Herrero-Aguayo V, et al. Among authors: lopez canovas jl. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e469-e484. doi: 10.1210/clinem/dgaa580. J Clin Endocrinol Metab. 2021. PMID: 32841353
Dysregulation of splicing variants and spliceosome components in breast cancer.
Gahete MD, Herman-Sanchez N, Fuentes-Fayos AC, Lopez-Canovas JL, Luque RM. Gahete MD, et al. Among authors: lopez canovas jl. Endocr Relat Cancer. 2022 Aug 1;29(9):R123-R142. doi: 10.1530/ERC-22-0019. Print 2022 Sep 1. Endocr Relat Cancer. 2022. PMID: 35728261 Free article. Review.
Dysregulation of the miRNome unveils a crosstalk between obesity and prostate cancer: miR-107 asa personalized diagnostic and therapeutic tool.
Herrero-Aguayo V, Sáez-Martínez P, Jiménez-Vacas JM, Moreno-Montilla MT, Montero-Hidalgo AJ, Pérez-Gómez JM, López-Canovas JL, Porcel-Pastrana F, Carrasco-Valiente J, Anglada FJ, Gómez-Gómez E, Yubero-Serrano EM, Ibañez-Costa A, Herrera-Martínez AD, Sarmento-Cabral A, Gahete MD, Luque RM. Herrero-Aguayo V, et al. Among authors: lopez canovas jl. Mol Ther Nucleic Acids. 2022 Feb 12;27:1164-1178. doi: 10.1016/j.omtn.2022.02.010. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35282415 Free PMC article.
Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma.
López-Cánovas JL, Del Rio-Moreno M, García-Fernandez H, Jiménez-Vacas JM, Moreno-Montilla MT, Sánchez-Frias ME, Amado V, L-López F, Fondevila MF, Ciria R, Gómez-Luque I, Briceño J, Nogueiras R, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD. López-Cánovas JL, et al. Cancer Lett. 2021 Jan 1;496:72-83. doi: 10.1016/j.canlet.2020.10.010. Epub 2020 Oct 8. Cancer Lett. 2021. PMID: 33038489
Signaling pathways in hepatocellular carcinoma.
Garcia-Lezana T, Lopez-Canovas JL, Villanueva A. Garcia-Lezana T, et al. Among authors: lopez canovas jl. Adv Cancer Res. 2021;149:63-101. doi: 10.1016/bs.acr.2020.10.002. Epub 2020 Nov 24. Adv Cancer Res. 2021. PMID: 33579428 Review.
PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing.
López-Cánovas JL, Hermán-Sánchez N, Del Rio-Moreno M, Fuentes-Fayos AC, Lara-López A, Sánchez-Frias ME, Amado V, Ciria R, Briceño J, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD. López-Cánovas JL, et al. Exp Mol Med. 2023 Jan;55(1):132-142. doi: 10.1038/s12276-022-00917-7. Epub 2023 Jan 6. Exp Mol Med. 2023. PMID: 36609600 Free PMC article.
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing.
López-Cánovas JL, Hermán-Sánchez N, Moreno-Montilla MT, Del Rio-Moreno M, Alors-Perez E, Sánchez-Frias ME, Amado V, Ciria R, Briceño J, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD. López-Cánovas JL, et al. Clin Transl Med. 2022 Nov;12(11):e1102. doi: 10.1002/ctm2.1102. Clin Transl Med. 2022. PMID: 36419260 Free PMC article.