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Toxicity of Necrostatin-1 in Parkinson's Disease Models.
Alegre-Cortés E, Muriel-González A, Canales-Cortés S, Uribe-Carretero E, Martínez-Chacón G, Aiastui A, López de Munain A, Niso-Santano M, Gonzalez-Polo RA, Fuentes JM, Yakhine-Diop SMS. Alegre-Cortés E, et al. Among authors: lopez de munain a. Antioxidants (Basel). 2020 Jun 15;9(6):524. doi: 10.3390/antiox9060524. Antioxidants (Basel). 2020. PMID: 32549347 Free PMC article.
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway.
Bravo-San Pedro JM, Niso-Santano M, Gómez-Sánchez R, Pizarro-Estrella E, Aiastui-Pujana A, Gorostidi A, Climent V, López de Maturana R, Sanchez-Pernaute R, López de Munain A, Fuentes JM, González-Polo RA. Bravo-San Pedro JM, et al. Among authors: lopez de munain a, lopez de maturana r. Cell Mol Life Sci. 2013 Jan;70(1):121-36. doi: 10.1007/s00018-012-1061-y. Epub 2012 Jul 8. Cell Mol Life Sci. 2013. PMID: 22773119
The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts.
Bravo-San Pedro JM, Gómez-Sánchez R, Niso-Santano M, Pizarro-Estrella E, Aiastui-Pujana A, Gorostidi A, Climent V, López de Maturana R, Sanchez-Pernaute R, López de Munain A, Fuentes JM, González-Polo RA. Bravo-San Pedro JM, et al. Among authors: lopez de munain a, lopez de maturana r. Autophagy. 2012 Oct;8(10):1537-9. doi: 10.4161/auto.21270. Epub 2012 Aug 23. Autophagy. 2012. PMID: 22914360 Free PMC article.
Murine muscle engineered from dermal precursors: an in vitro model for skeletal muscle generation, degeneration, and fatty infiltration.
García-Parra P, Naldaiz-Gastesi N, Maroto M, Padín JF, Goicoechea M, Aiastui A, Fernández-Morales JC, García-Belda P, Lacalle J, Álava JI, García-Verdugo JM, García AG, Izeta A, López de Munain A. García-Parra P, et al. Among authors: lopez de munain a. Tissue Eng Part C Methods. 2014 Jan;20(1):28-41. doi: 10.1089/ten.TEC.2013.0146. Epub 2013 Jun 22. Tissue Eng Part C Methods. 2014. PMID: 23631552 Free PMC article.
Leucine-rich repeat kinase 2 modulates cyclooxygenase 2 and the inflammatory response in idiopathic and genetic Parkinson's disease.
Lopez de Maturana R, Aguila JC, Sousa A, Vazquez N, Del Rio P, Aiastui A, Gorostidi A, Lopez de Munain A, Sanchez-Pernaute R. Lopez de Maturana R, et al. Among authors: lopez de munain a. Neurobiol Aging. 2014 May;35(5):1116-24. doi: 10.1016/j.neurobiolaging.2013.11.018. Epub 2013 Nov 22. Neurobiol Aging. 2014. PMID: 24360742
G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy.
Yakhine-Diop SM, Bravo-San Pedro JM, Gómez-Sánchez R, Pizarro-Estrella E, Rodríguez-Arribas M, Climent V, Aiastui A, López de Munain A, Fuentes JM, González-Polo RA. Yakhine-Diop SM, et al. Among authors: lopez de munain a. Toxicology. 2014 Oct 3;324:1-9. doi: 10.1016/j.tox.2014.07.001. Epub 2014 Jul 10. Toxicology. 2014. PMID: 25017139
Muscle wasting in myotonic dystrophies: a model of premature aging.
Mateos-Aierdi AJ, Goicoechea M, Aiastui A, Fernández-Torrón R, Garcia-Puga M, Matheu A, López de Munain A. Mateos-Aierdi AJ, et al. Among authors: lopez de munain a. Front Aging Neurosci. 2015 Jul 9;7:125. doi: 10.3389/fnagi.2015.00125. eCollection 2015. Front Aging Neurosci. 2015. PMID: 26217220 Free PMC article. Review.
355 results