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ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties.
Orozco C, de Los Rios C, Arias E, León R, García AG, Marco JL, Villarroya M, López MG. Orozco C, et al. Among authors: lopez mg. J Pharmacol Exp Ther. 2004 Sep;310(3):987-94. doi: 10.1124/jpet.104.068189. Epub 2004 Apr 26. J Pharmacol Exp Ther. 2004. PMID: 15111641
New multipotent tetracyclic tacrines with neuroprotective activity.
Marco-Contelles J, León R, de los Ríos C, García AG, López MG, Villarroya M. Marco-Contelles J, et al. Among authors: lopez mg. Bioorg Med Chem. 2006 Dec 15;14(24):8176-85. doi: 10.1016/j.bmc.2006.09.025. Epub 2006 Sep 26. Bioorg Med Chem. 2006. PMID: 17005406
398 results