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Page 1
Design of novel antitumor DNA alkylating agents: the benzacronycine series.
David-Cordonnier MH, Laine W, Gaslonde T, Michel S, Tillequin F, Koch M, Léonce S, Pierré A, Bailly C. David-Cordonnier MH, et al. Among authors: leonce s. Curr Med Chem Anticancer Agents. 2004 Mar;4(2):83-92. doi: 10.2174/1568011043482115. Curr Med Chem Anticancer Agents. 2004. PMID: 15032716 Review.
Acronycine derivatives as promising antitumor agents.
Guilbaud N, Léonce S, Tillequin F, Koch M, Hickman JA, Pierré A. Guilbaud N, et al. Among authors: leonce s. Anticancer Drugs. 2002 Jun;13(5):445-9. doi: 10.1097/00001813-200206000-00002. Anticancer Drugs. 2002. PMID: 12045455 Review.
Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1.
David-Cordonnier MH, Laine W, Joubert A, Tardy C, Goossens JF, Kouach M, Briand G, Thi Mai HD, Michel S, Tillequin F, Koch M, Leonce S, Pierre A, Bailly C. David-Cordonnier MH, et al. Among authors: leonce s. Eur J Biochem. 2003 Jul;270(13):2848-59. doi: 10.1046/j.1432-1033.2003.03663.x. Eur J Biochem. 2003. PMID: 12823555 Free article.
Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.
Thi Mai HD, Gaslonde T, Michel S, Tillequin F, Koch M, Bongui JB, Elomri A, Seguin E, Pfeiffer B, Renard P, David-Cordonnier MH, Laine W, Bailly C, Kraus-Berthier L, Léonce S, Hickman JA, Pierré A. Thi Mai HD, et al. Among authors: leonce s. J Med Chem. 2003 Jul 3;46(14):3072-82. doi: 10.1021/jm030790y. J Med Chem. 2003. PMID: 12825945
Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.
Do Q, Tian W, Yougnia R, Gaslonde T, Pfeiffer B, Pierré A, Léonce S, Kraus-Berthier L, David-Cordonnier MH, Depauw S, Lansiaux A, Mazinghien R, Koch M, Tillequin F, Michel S, Dufat H. Do Q, et al. Among authors: leonce s. Bioorg Med Chem. 2009 Mar 1;17(5):1918-27. doi: 10.1016/j.bmc.2009.01.062. Epub 2009 Jan 31. Bioorg Med Chem. 2009. PMID: 19217791
Influence of the stereoisomeric position of the reactive acetate groups of the benzo[b]acronycine derivative S23906-1 on its DNA alkylation, helix-opening, cytotoxic, and antitumor activities.
Depauw S, Gaslonde T, Léonce S, Kraus-Berthier L, Laine W, Lenglet G, Chiaroni A, Pfeiffer B, Bailly C, Michel S, Tillequin F, Pierré A, David-Cordonnier MH. Depauw S, et al. Among authors: leonce s. Mol Pharmacol. 2009 Dec;76(6):1172-85. doi: 10.1124/mol.109.057554. Epub 2009 Sep 14. Mol Pharmacol. 2009. PMID: 19752199
127 results