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Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection.
Sacha JB, Giraldo-Vela JP, Buechler MB, Martins MA, Maness NJ, Chung C, Wallace LT, León EJ, Friedrich TC, Wilson NA, Hiraoka A, Watkins DI. Sacha JB, et al. Among authors: leon ej. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9791-6. doi: 10.1073/pnas.0813106106. Epub 2009 May 28. Proc Natl Acad Sci U S A. 2009. PMID: 19478057 Free PMC article.
Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virus.
Burwitz BJ, Wu HL, Reed JS, Hammond KB, Newman LP, Bimber BN, Nimiyongskul FA, Leon EJ, Maness NJ, Friedrich TC, Yokoyama M, Sato H, Matano T, O'Connor DH, Sacha JB. Burwitz BJ, et al. Among authors: leon ej. J Virol. 2014 Mar;88(6):3598-604. doi: 10.1128/JVI.03304-13. Epub 2013 Dec 26. J Virol. 2014. PMID: 24371068 Free PMC article.
Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques.
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, Colgin LM, Axthelm M, Messaoudi I, Sacha JB, Burton DR, Forthal DN, Hessell AJ, Haigwood NL. Jaworski JP, et al. Among authors: leon ej. J Virol. 2013 Oct;87(19):10447-59. doi: 10.1128/JVI.00049-13. Epub 2013 Jul 24. J Virol. 2013. PMID: 23885083 Free PMC article.
CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.
Loffredo JT, Friedrich TC, León EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. Loffredo JT, et al. Among authors: leon ej. PLoS One. 2007 Nov 14;2(11):e1152. doi: 10.1371/journal.pone.0001152. PLoS One. 2007. PMID: 18000532 Free PMC article.
Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques.
Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O'Connor DH, Allison DB, Watkins DI. Valentine LE, et al. Among authors: leon ej. J Virol. 2009 Nov;83(22):11514-27. doi: 10.1128/JVI.01298-09. Epub 2009 Sep 2. J Virol. 2009. PMID: 19726517 Free PMC article.
Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.
Friedrich TC, Valentine LE, Yant LJ, Rakasz EG, Piaskowski SM, Furlott JR, Weisgrau KL, Burwitz B, May GE, León EJ, Soma T, Napoe G, Capuano SV 3rd, Wilson NA, Watkins DI. Friedrich TC, et al. Among authors: leon ej. J Virol. 2007 Apr;81(7):3465-76. doi: 10.1128/JVI.02392-06. Epub 2007 Jan 24. J Virol. 2007. PMID: 17251286 Free PMC article.
Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication.
Loffredo JT, Bean AT, Beal DR, León EJ, May GE, Piaskowski SM, Furlott JR, Reed J, Musani SK, Rakasz EG, Friedrich TC, Wilson NA, Allison DB, Watkins DI. Loffredo JT, et al. Among authors: leon ej. J Virol. 2008 Feb;82(4):1723-38. doi: 10.1128/JVI.02084-07. Epub 2007 Dec 5. J Virol. 2008. PMID: 18057253 Free PMC article.
Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques.
Maness NJ, Yant LJ, Chung C, Loffredo JT, Friedrich TC, Piaskowski SM, Furlott J, May GE, Soma T, León EJ, Wilson NA, Piontkivska H, Hughes AL, Sidney J, Sette A, Watkins DI. Maness NJ, et al. Among authors: leon ej. J Virol. 2008 Jun;82(11):5245-54. doi: 10.1128/JVI.00292-08. Epub 2008 Apr 2. J Virol. 2008. PMID: 18385251 Free PMC article.
34 results