Kyle AH - Search Results

1

DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost.

Wang T, Kyle AH, Baker JHE, Liu NA, Banáth JP, Minchinton AI. Wang T, et al. Among authors: kyle ah. Sci Rep. 2023 Aug 1;13(1):12429. doi: 10.1038/s41598-023-39649-7. Sci Rep. 2023. PMID: 37528151 Free PMC article.

2

Targeting quiescent tumor cells via oxygen and IGF-I supplementation.

Kyle AH, Baker JH, Minchinton AI. Kyle AH, et al. Cancer Res. 2012 Feb 1;72(3):801-9. doi: 10.1158/0008-5472.CAN-11-3059. Epub 2011 Dec 12. Cancer Res. 2012. PMID: 22158947

3

Tissue penetration and activity of camptothecins in solid tumor xenografts.

Kyle AH, Baker JH, Gandolfo MJ, Reinsberg SA, Minchinton AI. Kyle AH, et al. Mol Cancer Ther. 2014 Nov;13(11):2727-37. doi: 10.1158/1535-7163.MCT-14-0475. Epub 2014 Aug 20. Mol Cancer Ther. 2014. PMID: 25143448

4

Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically.

Chafe SC, McDonald PC, Saberi S, Nemirovsky O, Venkateswaran G, Burugu S, Gao D, Delaidelli A, Kyle AH, Baker JHE, Gillespie JA, Bashashati A, Minchinton AI, Zhou Y, Shah SP, Dedhar S. Chafe SC, et al. Among authors: kyle ah. Cancer Immunol Res. 2019 Jul;7(7):1064-1078. doi: 10.1158/2326-6066.CIR-18-0657. Epub 2019 May 14. Cancer Immunol Res. 2019. PMID: 31088846

5

Targeting the tumour vasculature: exploitation of low oxygenation and sensitivity to NOS inhibition by treatment with a hypoxic cytotoxin.

Baker JH, Kyle AH, Bartels KL, Methot SP, Flanagan EJ, Balbirnie A, Cran JD, Minchinton AI. Baker JH, et al. Among authors: kyle ah. PLoS One. 2013 Oct 28;8(10):e76832. doi: 10.1371/journal.pone.0076832. eCollection 2013. PLoS One. 2013. PMID: 24204680 Free PMC article.

6

Carbogen breathing after irradiation enhances the effectiveness of tirapazamine in SiHa tumors but not SCCVII tumors in mice.

Minchinton AI, Tonn DA, Sutherland DP, Kyle AH. Minchinton AI, et al. Among authors: kyle ah. Radiat Res. 2002 Jul;158(1):94-100. doi: 10.1667/0033-7587(2002)158[0094:cbaiet]2.0.co;2. Radiat Res. 2002. PMID: 12071808

7

Tumor distribution of bromodeoxyuridine-labeled cells is strongly dose dependent.

Kyle AH, Huxham LA, Baker JH, Burston HE, Minchinton AI. Kyle AH, et al. Cancer Res. 2003 Sep 15;63(18):5707-11. Cancer Res. 2003. PMID: 14522888

8

Microregional effects of gemcitabine in HCT-116 xenografts.

Huxham LA, Kyle AH, Baker JH, Nykilchuk LK, Minchinton AI. Huxham LA, et al. Among authors: kyle ah. Cancer Res. 2004 Sep 15;64(18):6537-41. doi: 10.1158/0008-5472.CAN-04-0986. Cancer Res. 2004. PMID: 15374965

9

Tirapazamine causes vascular dysfunction in HCT-116 tumour xenografts.

Huxham LA, Kyle AH, Baker JH, McNicol KL, Minchinton AI. Huxham LA, et al. Among authors: kyle ah. Radiother Oncol. 2006 Feb;78(2):138-45. doi: 10.1016/j.radonc.2006.01.002. Epub 2006 Feb 7. Radiother Oncol. 2006. PMID: 16455148

10

Vascular-specific quantification in an in vivo Matrigel chamber angiogenesis assay.

Baker JH, Huxham LA, Kyle AH, Lam KK, Minchinton AI. Baker JH, et al. Among authors: kyle ah. Microvasc Res. 2006 Mar;71(2):69-75. doi: 10.1016/j.mvr.2006.01.002. Epub 2006 Mar 20. Microvasc Res. 2006. PMID: 16545400

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